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首页> 外文期刊>Radiation Protection Dosimetry >CT DOSIMETRY FOR THE AUSTRALIAN COHORT DATA LINKAGE STUDY
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CT DOSIMETRY FOR THE AUSTRALIAN COHORT DATA LINKAGE STUDY

机译：澳大利亚队列数据联系研究的CT剂量测定

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摘要

Children undergoing computed tomography (CT) scans have an increased risk of cancer in subsequent years, but it is unclear how much of the excess risk is due to reverse causation bias or confounding, rather than to causal effects of ionising radiation. An examination of the relationship between excess cancer risk and organ dose can help to resolve these uncertainties. Accordingly, we have estimated doses to 33 different organs arising from over 900 000 CT scans between 1985 and 2005 in our previously described cohort of almost 12 million Australians aged 0-19 years. We used a multi-tiered approach, starting with Medicare billing details for government-funded scans. We reconstructed technical parameters from national surveys, clinical protocols, regulator databases and peer-reviewed literature to estimate almost 28 000 000 individual organ doses. Doses were age-dependent and tended to decrease over time due to technological improvements and optimisation.
机译：正在进行计算机断层扫描的儿童（CT）扫描随后几年癌症风险增加，但目前尚不清楚患有逆转偏差或混淆，而不是导致电离辐射的因果效应是多少。对多余癌症风险和器官剂量之间的关系的检查可以有助于解决这些不确定性。因此，我们在1985年至2005年间，我们在1985年至2005年间在我们之前描述的近1200万澳大利亚人的队伍之间以超过900 000ct扫描产生的33种不同器官的剂量。我们使用了一种多层方法，从医疗保险结算详情开始，以获得政府资助的扫描。我们从国家调查，临床协议，监管数据库和同行评审文献中重建了技术参数，以估计近28000 000个单独器官剂量。由于技术改善和优化，剂量依赖于年龄依赖性，并趋于减少时间。

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  • 来源
    《Radiation Protection Dosimetry》 |2020年第4期|423-438|共16页
  • 作者

    Zoe Brady; Anna Forsythe; Jasmine McBain-Miller; Katrina J. Scurrah; Nicolas Smoll; Yaqi Lin; Choonsik Lee; Amy Berrington de Gonzalez; Leo J. Roberts; John D. Mathews;

  • 作者单位

    Melbourne School of Population and Global Health The University of Melbourne Parkville Victoria Australia Department of Radiology and Nuclear Medicine Alfred Health Melbourne Victoria Australia;

    Melbourne School of Population and Global Health The University of Melbourne Parkville Victoria Australia;

    Melbourne School of Population and Global Health The University of Melbourne Parkville Victoria Australia;

    Melbourne School of Population and Global Health The University of Melbourne Parkville Victoria Australia;

    Melbourne School of Population and Global Health The University of Melbourne Parkville Victoria Australia;

    Melbourne School of Population and Global Health The University of Melbourne Parkville Victoria Australia;

    Division of Cancer Epidemiology and Genetics National Cancer Institute National Institutes of Health Bethesda Maryland USA;

    Division of Cancer Epidemiology and Genetics National Cancer Institute National Institutes of Health Bethesda Maryland USA;

    Melbourne School of Population and Global Health The University of Melbourne Parkville Victoria Australia;

    Melbourne School of Population and Global Health The University of Melbourne Parkville Victoria Australia;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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