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首页> 外文期刊>Radiation Protection Dosimetry >SPECIFIC ABSORBED FRACTIONS IN THYROID DIAGNOSTICS AND TREATMENT: MONTE CARLO CALCULATION WITH PENELOPE
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SPECIFIC ABSORBED FRACTIONS IN THYROID DIAGNOSTICS AND TREATMENT: MONTE CARLO CALCULATION WITH PENELOPE

机译：甲状腺液诊断和治疗中的特定吸收馏分：带透视的蒙特卡罗计算

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摘要

In nuclear medicine, diagnostic and therapy procedures in which a certain radiopharntaceutical is administered to a patient are performed. An important point is the determination of the dose absorbed by the important organs of the patient due to these procedures. This dose depends on the particular radionuclide used and the so-called specific absorbed fractions. In this work, by means of Monte Carlo (MC) simulation, the specific absorbed fractions in case the thyroid gland acts as a source organ and for photon energies between 30 keV and 2 MeV have been determined. The computer code PENELOPE has been used as well as the adult male mathematical phantom provided with the distribution of this code. Three different simulation types were carried out. In one of them, only photon transport was considered. In the other two, electron transport was included, doing a detailed and a mixed simulation. In general, the fractions were estimated with uncertainties <9 %, for the mixed and detailed simulations, and <3 %, for the simulation in which only photons are included. For some target organs and, especially for energies <100 keV, the uncertainties found were larger. The results obtained here have been compared with those obtained by other authors using other MC codes. A good agreement has been found in 80 % of the cases.
机译：在核医学中，执行其中向患者施用某种放射性药物的诊断和治疗程序。重要的一点是，由于这些程序，需要确定患者重要器官吸收的剂量。该剂量取决于所使用的特定放射性核素和所谓的特定吸收分数。在这项工作中，通过蒙特卡洛（MC）模拟，已经确定了在甲状腺作为源器官和30 keV至2 MeV之间的光子能量的情况下的特定吸收分数。已使用计算机代码PENELOPE以及随该代码的发布一起提供的成年男性数学模型。进行了三种不同的仿真类型。其中之一仅考虑了光子传输。另外两个包括电子传输，进行了详细的混合模拟。通常，对于混合和详细模拟，分数的不确定度<9％，对于仅包含光子的模拟，不确定度<3％。对于某些靶器官，尤其是对于<100 keV的能量，发现的不确定性更大。将此处获得的结果与其他作者使用其他MC代码获得的结果进行了比较。在80％的案件中，已经达成了良好的共识。

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  • 来源
    《Radiation Protection Dosimetry》 |2012年第1期|p.41-49|共9页
  • 作者

    G. Diaz Londono; A. M. Lallena;

  • 作者单位

    Departamento de Fisica Atomica, Molecular y Nuclear, Universidad de Granada, E-18071 Granada,Spain,Departamento de Fisica, Universidad del Atlantico, Antigua via a Puerto Colombia km. 7, Barranquilla,Atlantico, Colombia;

    Departamento de Fisica Atomica, Molecular y Nuclear, Universidad de Granada, E-18071 Granada,Spain;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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