首页> 外文期刊>Journal of the Mass Spectrometry Society of Japan >Stereoisomer Discrimination of Some Amino Sugars: Chiral Recognition FAB Mass Spectrometry Coupled with The Enantiomer-Labeled Host Method
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Stereoisomer Discrimination of Some Amino Sugars: Chiral Recognition FAB Mass Spectrometry Coupled with The Enantiomer-Labeled Host Method

机译:某些氨基糖的立体异构体区分:手性识别FAB质谱与对映体标记的宿主方法

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摘要

FAB mass spectrometry coupled with the host-guest complexation method was used to distinguish some amino sugars (1-8) including glucosamine, galactosamine, and mannosamine, etc. The method characteristically used a 1:1 mixture of the chiral crown ether host whose enantiomer was isotopically labeled. Diastereomer differentiation of a given amino sugar salt (G~+) was simply measured with a given host pair (A or B)from the peak intensity ratio of the two diastereomeric host-guest complex ions as I[(H_RRRR+G)~+]/ I[(H_SSSS-d_6+G)~+]≡IRIS (abbreviation).
机译:FAB质谱结合主体-客体络合方法用于区分一些氨基糖(1-8),包括氨基葡萄糖,半乳糖胺和甘露糖胺等。该方法的特征在于使用对映体为1:1的手性冠醚主体的混合物被同位素标记。给定的氨基糖盐(G〜+)的非对映异构体分化是简单地使用给定的宿主对(A或B)从两个非对映主体-客体复合离子的峰强度比I [(H_RRRR + G)〜+ ] / I [(H_SSSS-d_6 + G)〜+]≡IRIS(缩写)。

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