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Exposure of biological preparations to radiofrequency electromagnetic fields under low gravity

机译:在低重力下将生物制剂暴露于射频电磁场

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摘要

There is interest as to whether the electromagnetic fields used in mobile radiotelephony might affect biological processes. Other weak fields such as gravity intervene in a number of physical and biological processes. Under appropriate in vitro conditions, the macroscopic self-organization of microtubules, a major cellular component, is triggered by gravity. We wished to investigate whether self-organization might also be affected by radiotelephone electromagnetic fields. Detecting a possible effect requires removing the obscuring effects triggered by gravity. A simple manner of doing this is by rotating the sample about the horizontal. However, if the external field does not also rotate with the sample, its possible effect might also be averaged down by rotation. Here, we describe an apparatus in which both the sample and an applied radiofrequency electromagnetic field (1.8 GHz) are stationary with respect to one another while undergoing horizontal rotation. The electromagnetic field profile within the apparatus has been measured and the apparatus tested by reproducing the in vitro behavior of microtubule preparations under conditions of weightlessness. Specific adsorption rates of electromagnetic energy within a sample are measured from the initial temperature rise the incident field causes. The apparatus can be readily adapted to expose samples to various other external fields and factors under conditions of weightlessness. © 2010 American Institute of Physics Article Outline INTRODUCTION EXPERIMENTAL APPARATUS General features Clinostat Radiofrequency field system TESTING Clinostat function Specific adsorption rates CONCLUSIONS
机译:人们关注移动无线电话中使用的电磁场是否会影响生物过程。其他弱领域,例如重力,也介入了许多物理和生物过程。在适当的体外条件下,微管(细胞的主要成分)的宏观自组织是由重力触发的。我们希望研究自组织是否也可能受到无线电话电磁场的影响。要检测可能的效果,需要消除重力引起的模糊效果。一种简单的方法是通过围绕水平方向旋转样品。但是,如果外部场也不随样本旋转,则其可能的影响也可能会因旋转而平均下来。在这里,我们描述了一种装置,其中样品和所施加的射频电磁场(1.8 GHz)在经历水平旋转的同时相对于彼此是静止的。通过在失重条件下再现微管制剂的体外行为,已经测量了装置内的电磁场分布并测试了装置。根据入射场引起的初始温度升高来测量样品中电磁能的比吸收率。该设备可以容易地适于在失重条件下将样品暴露于各种其他外部场和因素。 ©2010美国物理研究所文章大纲简介实验装置一般特征斜管调压器射频场系统测试斜管调压器功能特定吸附率结论

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  • 来源
    《Review of Scientific Instruments》 |2010年第11期|p.1-5|共5页
  • 作者单位

    Direction des Sciences de la Matière, Institut Nanosciences et Cryogénie, Service de Chimie Inorganique et Biologique, Laboratoire de Résonances Magnétiques, CEA Grenoble, 17 Avenue des Martyrs, 38054 Grenoble, France;

    Direction des Sciences de la Matière, Institut Nanosciences et Cryogénie, Service de Chimie Inorganique et Biologique, Laboratoire de Résonances Magnétiques, CEA Grenoble, 17 Avenue des Martyrs, 38054 Grenoble, France;

    Direction des Sciences de la Matière, Institut Nanosciences et Cryogénie, Service de Chimie Inorganique et Biologique, Laboratoire de Résonances Magnétiques, CEA Grenoble, 17 Avenue des Martyrs, 38054 Grenoble, France;

    Direction des Sciences du Vivant, Institut en Recherches et Technologies des Sciences du Vivant, Laboratoire Biopuce, CEA Grenoble, 17 Avenue des Martyrs, 38054 Grenoble, France;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    adsorption; biological effects of fields; biological effects of microwaves; biological specimen preparation; biomagnetism; cellular effects of radiation; zero gravity experiments;

    机译:吸附;场的生物效应;微波的生物效应;生物标本的制备;生物磁性;辐射的细胞效应;零重力实验;

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