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Apparatus for simulating dynamic interactions between the spinal cord and soft-coupled intradural implants

机译：用于模拟脊髓与硬耦合硬膜内植入物之间动态相互作用的装置

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摘要

We have designed, built, and tested an apparatus used for investigating the biomechanical response of a novel intradural spinal cord stimulator to the simulated physiological movement of the spinal cord within the thecal sac. In this apparatus, the rostral-caudal displacements of an anthropomorphic spinal cord surrogate can be controlled with a resolution of approximately 0.1% of a target value for up to 107 lateral movement cycles occurring at a repetition rate of 2 Hz. Using this system, we have been able to determine that the restoring force of the stimulator's suspension system works in concert with the frictional coupling between the electrode array and the surrogate to overcome the 0.42 μN inertial force associated with the lateral motion of the array. The result is a positional stability of the array on the surrogate (in air) of better than 0.2 mm over ∼500 000 movement cycles. Design modifications that might lead to improved physiological performance are discussed.
机译：我们已经设计，建造和测试了一种用于研究新型硬膜内脊髓刺激器对鞘囊内脊髓的模拟生理运动的生物力学响应的设备。在这种装置中，拟人型脊髓替代物的鼻尾位移可以以目标值的大约0.1％的分辨率控制，重复率最高为10 7 个横向运动周期。 2赫兹使用该系统，我们已经能够确定刺激器悬挂系统的恢复力与电极阵列和替代物之间的摩擦耦合协同工作，从而克服了与阵列横向运动相关的0.42μN惯性力。结果是，在约500,000个运动周期内，阵列在空中（空中）的位置稳定性优于0.2 mm。讨论了可能导致改善生理性能的设计修改。

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