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Continuously Recording Radioactive Hemoglobinometer

机译:连续记录放射性血红蛋白仪

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摘要

A radioactive method, employing hemoglobin with incorporated Fe59, for continuously recording hemoglobin concentration in the blood of a living animal is described. This method records hemoglobin concentration independently of oxygenation of the blood and independently of the rate of blood flow through the apparatus. The only error that has been found in the method is statistical variation in the level of recording in accordance with the usual ``shot'' effect that is inherent in radioactive disintegrations. This statistical variation becomes less the greater the quantity of radioactive iron administered to the animal. For most purposes five microcuries per kilogram of Fe59 gives a satisfactory recording, and this quantity of radioactive iron is at least 50 times less than the maximal safe‐handling dose.
机译:描述了一种放射性方法,该方法采用掺有Fe59的血红蛋白连续记录活体动物血液中的血红蛋白浓度。该方法记录的血红蛋白浓度与血液的氧合作用无关,并且与通过设备的血流速率无关。在该方法中发现的唯一错误是根据放射性崩解固有的通常的``发射''效应,记录水平的统计变化。给予动物的放射性铁量越大,这种统计差异就越小。在大多数情况下,每千克Fe59中有5个微居里的汞可以令人满意地记录下来,而且这种放射性铁的量至少比最大安全处理剂量少50倍。

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