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Arsenic and human health: epidemiologic progress and public health implications

机译:砷与人类健康:流行病学进展及对公共健康的影响

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摘要

Elevated concentrations of arsenic in groundwater pose a public health threat to millions of people worldwide, including severely affected populations in South and Southeast Asia. Although arsenic is an established human carcinogen and has been associated with a multitude of health outcomes in epidemiologic studies, a mode of action has yet to be determined for some aspects of arsenic toxicity. Herein, we emphasize the role of recent genetic and molecular epidemiologic investigations of arsenic toxicity. Additionally, we discuss considerations for the public health impacts of arsenic exposure through drinking water with respect to primary and secondary prevention efforts.
机译:地下水中砷的浓度升高对全世界数以百万计的人构成公共健康威胁,其中包括南亚和东南亚受到严重影响的人口。尽管砷是已确定的人类致癌物,并已在流行病学研究中与多种健康结果相关联,但对于砷毒性的某些方面,尚未确定一种作用方式。在此,我们强调砷毒性的最新遗传和分子流行病学研究的作用。此外,我们讨论了关于一级和二级预防工作中通过饮用水接触砷对公共健康的影响的考虑因素。

著录项

  • 来源
    《Reviews on environmental health》 |2012年第4期|191-195|共5页
  • 作者单位

    Department of Health Studies, University of Chicago, 5841 S. Maryland Avenue, MC2007, Chicago, IL 60637, USA;

    Department of Health Studies, University of Chicago, Chicago, IL, USA;

    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    arsenic; asia; drinking water; human health.;

    机译:砷;亚洲;饮用水;人类健康。;

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