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The value of ecologic studies: mercury concentration in ambient air and the risk of autism

机译：生态研究的价值：环境空气中的汞浓度和自闭症的风险

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Ecologic studies of the spatial relationship between disease and sources of environmental contamination can help to ascertain the degree of risk to populations from contamination and to inform legislation to ameliorate the risk. Population risks associated with persistent low-level mercury exposure have recently begun to be of concern and current reports implicate environmental mercury as a potential contributor in the etiology of various developmental and neurodegenerative diseases including autism and Alzheimer's disease. In this demonstration of preliminary findings, we demonstrate for Bexar County Texas and Santa Clara County California, the hypothesis that the spatial structure of the occurrence of autism has a positive co-variation with the spatial structure of the distribution of mercury in ambient air. The relative risk of autism is greater in the geographic areas of higher levels of ambient mercury. We find that the higher levels of ambient mercury are geographically associated with point sources of mercury emission, such as coal-fired power plants and cement plants with coal-fired kilns. Although this does not indicate a cause, these results should not be dismissed, but rather seen as a preliminary step for generating a hypothesis for further investigation.
机译：对疾病与环境污染源之间的空间关系进行生态学研究，可以帮助确定人们受到污染的风险程度，并为改善这种风险提供法律依据。与持续的低水平汞暴露相关的人口风险最近开始受到关注，当前的报道暗示环境汞是包括自闭症和阿尔茨海默氏病在内的各种发展和神经退行性疾病的病因学的潜在贡献者。在这一初步发现的证明中，我们证明了德克萨斯州的贝克萨尔县和加利福尼亚的圣克拉拉县的假说，即自闭症发生的空间结构与周围空气中汞分布的空间结构呈正协变。在环境汞含量较高的地理区域，自闭症的相对风险更大。我们发现，较高的环境汞含量在地理上与汞排放的点源有关，例如燃煤发电厂和带有燃煤窑的水泥厂。尽管这并不表示原因，但不应忽略这些结果，而应将其视为生成假设以进行进一步研究的初步步骤。

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