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首页> 外文期刊>Reviews in Fish Biology and Fisheries >Zebrafish as a model organism for nutrition and growth: towards comparative studies of nutritional genomics applied to aquacultured fishes
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Zebrafish as a model organism for nutrition and growth: towards comparative studies of nutritional genomics applied to aquacultured fishes

机译：斑马鱼作为营养和生长的典范生物：用于水产养殖鱼类营养基因组学的比较研究

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摘要

Zebrafish (Danio rerio) is a common research model in fish studies of toxicology, developmental biology, neurobiology and molecular genetics; it has been proposed as a possible model organism for nutrition and growth studies in fish. The advantages of working with zebrafish in these areas are their small size, short generation time (12–14 weeks) and their capacity to produce numerous eggs (100–200 eggs/clutch). Since a wide variety of molecular tools and information are available for genomic analysis, zebrafish has also been proposed as a model for nutritional genomic studies in fish. The detailed study of every species employed as a model organism is important because these species are used to generalize how several biological processes occur in related organisms, and contribute considerably toward improving our understanding of the mechanisms involved in nutrition and growth. The objective of this review is to show the relevant aspects of the nutrition and growth in zebrafish that support its utility as a model organism for nutritional genomics studies. We made a particular emphasis that gene expression and genetic variants in response to zebrafish nutrition will shed light on similar processes in aquacultured fish.
机译：斑马鱼（Danio rerio）是鱼类的毒理学，发育生物学，神经生物学和分子遗传学研究中的常见研究模型；已经提出将其作为鱼类营养和生长研究的可能模式生物。在这些区域中使用斑马鱼的优势在于它们的体积小，生成时间短（12-14周）以及产生大量卵的能力（每个离合器100-200个卵）。由于有各种各样的分子工具和信息可用于基因组分析，因此斑马鱼也被提议作为鱼类营养基因组研究的模型。对用作模型生物的每个物种的详细研究很重要，因为这些物种用于概括相关生物中几种生物过程的发生方式，并有助于增进我们对营养和生长机制的理解。这篇综述的目的是显示斑马鱼营养和生长的相关方面，以支持斑马鱼作为营养基因组学研究的模型生物。我们特别强调，响应斑马鱼营养的基因表达和遗传变异将阐明水产养殖鱼类的类似过程。

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