p21 gene polymorphisms in systemic lupus erythematosus

E. K.-P. Kong W.-P. Chong W. H.-S. Wong C.-S. Lau; T.-M. Chan; P. K.-M. Ng; Y.-Q. Song; W. Mak; and Y.-L. Lau

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p21 gene polymorphisms in systemic lupus erythematosus

机译：系统性红斑狼疮p21基因多态性

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Objective. Cyclin-dependent kinase inhibitor 1A (p21) is a negative regulator in the cell cycle. Development of sex-linked lupus-like syndrome in p21?/? mice and reduced p21 gene expression in patients with systemic lupus erythematosus (SLE) compared with those in healthy controls suggested that p21 is a susceptibility gene of SLE. We investigated the same by a case-control association study.

机译：目的。细胞周期蛋白依赖性激酶抑制剂1A（p21）在细胞周期中是负调节剂。与健康对照组相比，系统性红斑狼疮（SLE）患者中p21 ？/？小鼠性连锁性狼疮样综合征的发展以及p21基因表达的降低表明p21是糖尿病的易感基因SLE。我们通过病例对照研究进行了调查。

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来源
《Rheumatology》 |2007年第2期|220-226|共7页
作者
E. K.-P. Kong W.-P. Chong W. H.-S. Wong C.-S. Lau; T.-M. Chan; P. K.-M. Ng; Y.-Q. Song; W. Mak; and Y.-L. Lau;
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作者单位

Department of Paediatrics and Adolescent Medicine;

Department of Medicine and;

Department of Genome Research Centre The Hong Kong Jockey Club Research Center The University of Hong Kong Pokfulam Hong Kong SAR China;

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1. p21 gene polymorphisms in systemic lupus erythematosus. [J] . Kong EK, Chong WP, Wong WH, Rheumatology . 2007,第2期

机译：系统性红斑狼疮p21基因多态性。
2. Peptidylarginine deiminase-4 gene polymorphisms are associated with systemic lupus erythematosus and lupus nephritis [J] . Massarenti L., Enevold C., Damgaard D., Scandinavian journal of rheumatology . 2019,第2期

机译：肽基质氨基酶-4基因多态性与Systemic Lupus红斑和狼疮性肾炎有关
3. Tumor necrosis factor gene polymorphisms are associated with systemic lupus erythematosus susceptibility or lupus nephritis in Mexican patients [J] . Ramirez-Bello Julian, Cadena-Sandoval Daniel, Flavio Mendoza-Rincon Jorge, Immunologic Research: A Selective Reference to Current Research and Practice . 2018,第3期

机译：肿瘤坏死因子基因多态性与墨西哥患者的Systemic Lupus红斑狼疮易感性或狼疮肾炎有关
4. Explainable Machine Learning applied to Single-Nucleotide Polymorphisms for Systemic Lupus Erythematosus Prediction [C] . Marc Jermaine Pontiveros, Geoffrey A. Solano, Cherica A. Tee, International Conference on Information, Intelligence, Systems and Applications . 2020

机译：可说明的机器学习适用于系统性狼疮性红斑预测的单核苷酸多态性
5. Investigating B cell and T cell Cognate Interactions in Systemic Lupus Erythematosus: A Novel System for the Study of Lupus Antigen-Specific T cells. [D] . Giles, Josephine Ruth. 2015

机译：研究系统性红斑狼疮中B细胞和T细胞同源相互作用：研究狼疮抗原特异性T细胞的新型系统。
6. Low apolipoprotein M serum levels correlate with Systemic lupus erythematosus disease activity and apolipoprotein M gene polymorphisms with Lupus [O] . Wenhan Du, Ting Shen, Hui Li, 2017

机译：载脂蛋白M血清水平低与系统性红斑狼疮疾病活动性相关以及与狼疮的载脂蛋白M基因多态性相关
7. p21 gene polymorphisms in systemic lupus erythematosus [O] . Y. -q. Song, W. Mak, Y. -l. Lau 2015

机译：p21基因多态性在系统性红斑狼疮中的表达

p21 gene polymorphisms in systemic lupus erythematosus

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