A Generalized QMRA Beta-Poisson Dose-Response Model

Xie Gang; Roiko Anne; Stratton Helen; Lemckert Charles; Dunn Peter K.; Mengersen Kerrie

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A Generalized QMRA Beta-Poisson Dose-Response Model

机译：广义QMRA Beta-泊松剂量反应模型

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Quantitative microbial risk assessment (QMRA) is widely accepted for characterizing the microbial risks associated with food, water, and wastewater. Single-hit dose-response models are the most commonly used dose-response models in QMRA. Denoting PI(d) as the probability of infection at a given mean dose d, a three-parameter generalized QMRA beta-Poisson dose-response model, PI(d|), is proposed in which the minimum number of organisms required for causing infection, K-min, is not fixed, but a random variable following a geometric distribution with parameter 0

机译：定量微生物风险评估（QMRA）用于表征与食物，水和废水有关的微生物风险。一次性命中剂量反应模型是QMRA中最常用的剂量反应模型。将PI（d）表示为在给定的平均剂量d下的感染可能性，提出了三参数广义QMRAβ-泊松剂量反应模型PI（d |），其中引起感染所需的最少生物量，K-min，不是固定的，而是一个遵循几何分布且参数0

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来源
《Risk analysis》 |2016年第10期|1948-1958|共11页
作者
Xie Gang; Roiko Anne; Stratton Helen; Lemckert Charles; Dunn Peter K.; Mengersen Kerrie;
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作者单位

Univ Sunshine Coast, Fac Sci Hlth Educ & Engn, Sunshine Coast, Qld, Australia|Griffith Univ, Smart Water Res Ctr, Southport, Qld, Australia;

Griffith Univ, Smart Water Res Ctr, Southport, Qld, Australia|Griffith Univ, Menzies Hlth Inst Queensland, Southport, Qld, Australia;

Griffith Univ, Smart Water Res Ctr, Southport, Qld, Australia;

Griffith Univ, Smart Water Res Ctr, Southport, Qld, Australia|Griffith Univ, Sch Engn, Southport, Qld, Australia;

Univ Sunshine Coast, Fac Sci Hlth Educ & Engn, Sunshine Coast, Qld, Australia;

Queensland Univ Technol, Fac Sci & Engn, Brisbane, Qld, Australia;

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正文语种 eng
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关键词
A generalized beta-Poisson model; approximate Bayesian computation; QMRA; single-hit beta-Poisson models;

机译：广义β-泊松模型;近似贝叶斯计算;QMRA;单命中β-泊松模型;

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专利

1. Harnessing the Theoretical Foundations of the Exponential and Beta-Poisson Dose-Response Models to Quantify Parameter Uncertainty Using Markov Chain Monte Carlo [J] . Philip J. Schmidt, Katarina D. M. Pintar, Aamir M. Fazil, Risk analysis . 2013,第9期

机译：利用马尔可夫链蒙特卡洛方法利用指数模型和Beta-泊松剂量反应模型的理论基础来量化参数不确定性
2. Comment on "Guidelines for Use of the Approximate Beta-Poisson Dose-Response Model": Previously Published Guidelines Continue to be Ignored [J] . Schmidt Philip J. Risk analysis . 2017,第2期

机译：对“使用近似Beta-泊松剂量反应模型的指南”的评论：先前发布的指南仍将被忽略
3. Guidelines for Use of the Approximate Beta-Poisson Dose-Response Model [J] . Xie Gang, Roiko Anne, Stratton Helen, Risk analysis . 2017,第7期

机译：近似Beta-泊松剂量反应模型的使用指南
4. QMRA Wiki: An Educational Tool for Interdisciplinary Teaching of Risk Modeling in Engineering Curricula [C] . Mark H. Weir, Jade Mitchell, Julie Libarkin, American Society for Engineering Education Annual Conference and Exposition . 2018

机译：QMRA Wiki：工程课程中风险建模跨学科教学的教育工具
5. QMRA: Exposure model sensitivity to input parameters, critical review of dose-response models, and application in assessing risk of aging drinking water distribution systems [D] . Van Abel, Nicole A. 2014

机译：QMRA：暴露模型对输入参数的敏感性，剂量反应模型的严格审查，以及在评估饮用水分配系统老化的风险中的应用
6. Development of a microbial dose response visualization and modelling application for QMRA modelers and educators [O] . Mark H. Weir, Jade Mitchell, William Flynn, -1

机译：为QMRA建模者和教育者开发的微生物剂量响应可视化和建模应用程序
7. Guidelines for Use of the Approximate Beta-Poisson Dose-Response Model [O] . Gang Xie, Anne Roiko, Helen Stratton, 2016

机译：使用近似β-泊松剂量 - 响应模型的指导

A Generalized QMRA Beta-Poisson Dose-Response Model

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