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首页> 外文期刊>Russian journal of marine biology >Cholinergic Regulation of Body-Wall Muscle Contraction of the Ascidian Styela rustica (Linnaeus, 1767)
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Cholinergic Regulation of Body-Wall Muscle Contraction of the Ascidian Styela rustica (Linnaeus, 1767)

机译：海豚Styela Rusta的体壁肌肉收缩的胆碱能调节（Linnaeus，1767年）

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摘要

The regulation of body-wall muscle contraction in the ascidian Styela rustica was studied. Acetyl-choline (ACh, 1 -10 μM) induced a significant contraction of isolated muscle strips. The ACh-induced contractile response was potentiated and prolonged in the presence of proserine (15 uM), which confirms ace-tylcholinesterase activity in the S. rustica body-wall muscle. Atropine (1-100 μm, M-cholinoreceptor blocker) did not prevent the ACh-induced contractile response, while d-tubocurarine (1 -100 μM, N-choli-noreceptor blocker) progressively reduced muscle contraction induced by 10 μM ACh. Thus, neuromuscular transmission in the S. rustica body-wall muscle is mediated by nicotinic-like ACh-receptors. Procaine reduced ACh-induced (10 μM) muscle contraction. As well, our experiments showed spontaneous rhythmic contractile activity in isolated muscle strips of S. rustica. Atropine, d-tubocurarine, procaine, and proserine did not alter rhythmic activity. Myogenic automaticity is suggested as a possible cause of the rhythmic contraction of the ascidian body-wall muscle.
机译：研究了海豚Styela Rusta中体壁肌肉收缩的调节。乙酰胆碱（ACh，1 -10μM）引起离体肌肉条的明显收缩。 ACh诱导的收缩反应在脯氨酸（15 uM）的存在下被增强并延长，这证实了在锈菌链球菌体壁肌肉中乙酰胆碱酯酶的活性。阿托品（1-100μm，M-胆碱受体阻滞剂）不能阻止ACh诱导的收缩反应，而d-微管尿素（1 -100μM，N-胆碱-受体阻滞剂）逐渐减少10μMACh诱导的肌肉收缩。因此，质朴链球菌体壁肌肉中的神经肌肉传递是由烟碱样ACh受体介导的。普鲁卡因减少了ACh诱导的（10μM）肌肉收缩。同样，我们的实验还显示了在乡村链球菌分离的肌肉条中自发的节律性收缩活动。阿托品，d-微管尿素，普鲁卡因和脯氨酸不会改变节律活动。提示肌原性自动性是海鞘体壁肌肉节律性收缩的可能原因。

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