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首页> 外文期刊>Russian journal of marine biology >Chemical Composition of Ethanolic Extracts from some Seaweed Species of the South Indian Coastal Zone, their Antibacterial and Membrane-Stabilizing Activity
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Chemical Composition of Ethanolic Extracts from some Seaweed Species of the South Indian Coastal Zone, their Antibacterial and Membrane-Stabilizing Activity

机译：南印度沿海地区一些海藻种的乙醇提取物的化学成分，抗菌和膜稳定活性

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摘要

The present study was intended to investigate the presence of major chemical components in seaweed extracts by using of Fourier-transform infrared spectroscopy (FTIR) and to explore the antibacterial and in vitro anti-inflammatory (membrane stability) properties of ethanolic extracts of nine different seaweeds collected from the Ramewaram coastal region. Total flavonoid content (TFC) and total tannin content (TTC) of ethanolic extracts were determined using spectrometric method. Antimicrobial activity of ethanolic extracts was tested against six bacterial strains using the disc diffusion method. Study of the preliminary anti-inflammatory activity of seaweed extracts was performed by the HRBC membrane stabilization method. Turbinaria ornata shows the highest TFC and TTC among all the studied seaweed species. Significant differences were observed in anti-inflammatory activity of ethanolic extracts from various seaweeds investigated using the human red blood cell (HRBC) membrane stabilization method. HRBC membrane stabilization activity of ethanolic extracts of seaweeds exhibited dose dependency and increased with increasing concentration of the extract. Ethanolic extract of T. ornata had the strongest growth inhibition against Proteusmirabilis. FTIR spectroscopy analysis of three seaweeds provided a detailed report of major functional constituents and chemical components. It can be concluded that seaweeds are rich in polyphenols to which acquire potent antimicrobial and anti-inflammatory activity. Seaweed extracts are a major breakthrough for pharmaceutical application.
机译：本研究旨在通过使用傅里叶变换红外光谱（FTIR）来研究海藻提取物中主要化学成分的存在，并探讨九种不同海藻乙醇提取物的抗菌和体外抗炎（膜稳定性）性能从Ramewaram沿海地区收集。使用光谱法测定乙醇萃取物的总类黄酮含量（TFC）和总单宁含量（TTC）。使用盘扩散法针对六种细菌菌株测试乙醇萃取物的抗微生物活性。通过HRBC膜稳定法进行海藻提取物的初步抗炎活性的研究。 Turbinaria Ornata显示最高的TFC和TTC在所有学习的海藻物种中。使用人红细胞（HRBC）膜稳定法研究的各种海藻的乙醇提取物的抗炎活性观察到显着差异。海藻乙醇提取物的HRBC膜稳定活性表现出剂量依赖性，随着提取物浓度的增加而增加。 T. ornata的乙醇提取物对proteusmirabilis具有最强的生长抑制。三种海藻的FTIR光谱分析提供了具有主要功能性成分和化学成分的详细报道。可以得出结论，海藻含有丰富的多酚，可获得有效的抗菌和抗炎活性。海藻提取物是制药应用的重大突破。

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