AVERMECTIN AND ARTEMISININ: WEAPONS TO ANTIPARASITIC DISEASE-FREE TROPICAL WORLD

APARNA BANERJEE; RAJIB BANDOPADHYAY

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AVERMECTIN AND ARTEMISININ: WEAPONS TO ANTIPARASITIC DISEASE-FREE TROPICAL WORLD

机译：阿维菌素和青蒿素：抗寄生虫病无热带世界的武器

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Nobel Prize winning discovery of Avermectin by Campbell and Omura have drastically reduced the occurrence of river blindness and lymphatic filariasis, as well as showing effectiveness against an increasing number of various parasitic diseases. Tu's discovery of artemisinin extensively lowered the mortality rates for malaria patients. These two discoveries have lowered down millions of death annually in the tropical world. Global initiatives sponsored by WHO, non-governmental organizations (NGOs) and Governments set target of elimination of lymphatic filariasis and river blindness by 2025.

机译：坎贝尔和大村获得诺贝尔奖的阿维菌素的发现大大减少了河盲症和淋巴丝虫病的发生，并显示出对越来越多的各种寄生虫病的有效性。涂的青蒿素发现大大降低了疟疾患者的死亡率。这两个发现每年降低了热带世界的数百万人死亡。由世卫组织，非政府组织和政府发起的全球倡议设定了到2025年消除淋巴丝虫病和河盲症的目标。

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《Science and Culture》 |2017年第6期|148-151|共4页
作者
APARNA BANERJEE; RAJIB BANDOPADHYAY;
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UGC-Center of Advanced Study, Department of Botany, The University of Burdwan, Golapbag, Bardhaman-713104, West Bengal, India;

UGC-Center of Advanced Study, Department of Botany, The University of Burdwan, Golapbag, Bardhaman-713104, West Bengal, India;

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1. History of Avermectin and Ivermectin, with Notes on the History of Other Macrocyclic Lactone Antiparasitic Agents [J] . William C. Campbell Current Pharmaceutical Biotechnology . 2012,第6期

机译：阿维菌素和伊维菌素的病史，以及其他大环内酯抗寄生虫药史的注释
2. TOTAL SYNTHESIS OF THE ANTIPARASITIC AGENT AVERMECTIN B-1A [J] . White JD., Dantanarayana AP., Fox CMJ., Journal of the American Chemical Society . 1995,第7期

机译：合成抗寄生虫剂AVERMECTB-1A
3. Reflections on the Nobel Prize for Medicine 2015 The Public Health Legacy and Impact of Avermectin and Artemisinin [J] . Molyneux David H., Ward Steve A. Trends In Parasitology . 2015,第12期

机译：对2015年诺贝尔医学奖的反思阿维菌素和青蒿素的公共卫生遗产和影响
4. Information Aspects of Manufacturing, Registering and Distributing The Antiparasitic Avermectin Drugs for Veterinary and Crop Protection Use [C] . Alexander Victorov, Victor Drinyaev Third Asian Conference for Information Technology in Agriculture, Oct 26-28, 2002, Beijing, China . 2002

机译：制造，注册和分发兽用和作物保护用抗寄生虫阿维菌素药物的信息方面
5. Taking Artemisinin to Clinical Anticancer Applications: Design, Synthesis and Characterization of pH-responsive Artemisinin Dimer Derivatives in Lipid Nanoparticles [D] . Zhang, Yitong. 2015

机译：将青蒿素用于临床抗癌应用：脂质纳米颗粒中pH响应型青蒿素二聚体衍生物的设计，合成和表征
6. A second branched-chain alpha-keto acid dehydrogenase gene cluster (bkdFGH) from Streptomyces avermitilis: its relationship to avermectin biosynthesis and the construction of a bkdF mutant suitable for the production of novel antiparasitic avermectins. [O] . C D Denoya, R W Fedechko, E W Hafner, 1995

机译：来自阿维链霉菌的第二个支链α-酮酸脱氢酶基因簇（bkdFGH）：其与阿维菌素生物合成的关系以及适于生产新型抗寄生虫阿维菌素的bkdF突变体的构建。
7. A second branched-chain alpha-keto acid dehydrogenase gene cluster (bkdFGH) from Streptomyces avermitilis: its relationship to avermectin biosynthesis and the construction of a bkdF mutant suitable for the production of novel antiparasitic avermectins. [O] . Denoya, C D, Fedechko, R W, Hafner, E W, 1995

机译：来自阿维链霉菌的第二个支链α-酮酸脱氢酶基因簇（bkdFGH）：其与阿维菌素生物合成的关系以及适于生产新型抗寄生虫阿维菌素的bkdF突变体的构建。
8. Pesticide Fact Sheet Number 89.2: Avermectin B1 [R] . 1990

机译：农药概况介绍编号89.2：阿维菌素B1

AVERMECTIN AND ARTEMISININ: WEAPONS TO ANTIPARASITIC DISEASE-FREE TROPICAL WORLD

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