INTEGRATION OF BIOINFORMATIC FLOW FROM GENOME TO PHENOME : THE GAP IS STILL OPEN

P SHARMA; O P GUPTA; R SINGH; I SHARMA

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INTEGRATION OF BIOINFORMATIC FLOW FROM GENOME TO PHENOME : THE GAP IS STILL OPEN

机译：生物信息流从基因组到现象的整合：缺口仍然存在

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Recent advances in technology and the development of high-throughput research in the field of biotechnology is beginning to suffer from data overload. Precise data integration requires the formal annotation of data with relational terms, and this is an essential driver behind applications of bioinformatics in the development of systems biology. This has led to the development of bioinformatics which is an integration of biology and information technology. It has been originated to fulfil the need of structuring ever-increasing 'omics' based biological information to enable logical interrogation.

机译：生物技术领域的最新技术进展和高通量研究的发展开始遭受数据过载的困扰。精确的数据集成需要使用关系术语对数据进行正式注释，这是在系统生物学发展中应用生物信息学的重要推动力。这导致了生物信息学的发展，它是生物学和信息技术的结合。它的产生是为了满足构造越来越多的基于“组学”的生物学信息以进行逻辑询问的需求。

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《Science and Culture》 |2014年第2期|42-43|共2页
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P SHARMA; O P GUPTA; R SINGH; I SHARMA;
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1. The federated database--a basis for biobank-based post-genome studies, integrating phenome and genome data from 600,000 twin pairs in Europe. [J] . Muilu J, Peltonen L, Litton JE European journal of human genetics: EJHG . 2007,第7期

机译：联邦数据库-基于生物库的后基因组研究的基础，整合了来自欧洲60万对双胞胎的表型和基因组数据。
2. An integrative functional genomics framework for effective identification of novel regulatory variants in genome–phenome studies [J] . Junfei Zhao, Feixiong Cheng, Peilin Jia, Genome Medicine . 2018,第1期

机译：一个整合的功能基因组学框架，可有效识别基因组-现象研究中的新型调控变异
3. Where genome meets phenome: Rationale for integrating genetic and protein biomarkers in the diagnosis and management of dilated cardiomyopathy and heart failure [J] . PiranS., LiuP., MoralesA., Journal of the American College of Cardiology . 2012,第4期

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4. A BIOINFORMATICS APPROACH TO GENOME TO PHENOME PREDICTIONS IN CHO CELL LINES [C] . Derrick Scott Cell culture engineering conference . 2018

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5. Bridging the Genomic Gaps: Genome-Scale Metabolic Network Tools for Bioinformatics Analyses [D] . Cuevas, Daniel Ablang. 2018

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6. An integrative functional genomics framework for effective identification of novel regulatory variants in genome–phenome studies [O] . Junfei Zhao, Feixiong Cheng, Peilin Jia, 2018

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7. Multi-omics integration of the phenome, transcriptome and genome highlights genes and pathways relevant to essential tremor [O] . Calwing Liao, Faezeh Sarayloo, Daniel Rochefort, 2019

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INTEGRATION OF BIOINFORMATIC FLOW FROM GENOME TO PHENOME : THE GAP IS STILL OPEN

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