Drugs and Drug Targets Against the Malarial Parasites

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Drugs and Drug Targets Against the Malarial Parasites

机译：对抗疟原虫的药物和药物靶标

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While giving an introduction about malaria, Prof. Padmanaban spoke on morbidity and mortality associated with malaria. There occurs more than a million deaths due to malaria. The four species of the malarial parasite are: Plasmodium falciparum, P. vivax, P. ovale and P. malariae. Out of them, P. falciparum is the most deadly parasite, which along with P. vivax is the causative agent of most cases of malaria.

机译：在介绍有关疟疾的同时，帕德马纳班教授谈到了与疟疾有关的发病率和死亡率。由于疟疾，死亡人数超过一百万。疟原虫的四个种类是：恶性疟原虫，间日疟原虫，卵圆形疟原虫和疟疾疟原虫。其中，恶性疟原虫是最致命的寄生虫，它与间日疟原虫一起是大多数疟疾病例的病原体。

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《Science and Culture》 |2010年第12期|p.569-570|共2页
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1. Sequencing of the malarial parasite genome reveals potential drug targets to combat malaria [J] . Luthra PM, Luthra R Current Science: A Fortnightly Journal of Research . 2003,第5期

机译：疟疾寄生虫基因组测序揭示了抗击疟疾的潜在药物靶标
2. Sequencing of the malarial parasite genome reveals potential drug targets to combat malaria [J] . Mehta Pratibha, Uthra Rajesh L. Current science . 2003,第05期

机译：疟疾寄生虫基因组测序揭示了抗击疟疾的潜在药物靶标
3. Glutathione S-Transferase of the Malarial Parasite Plasmodium falciparum: Characterization of a Potential Drug Target [J] . Petra Harwaldt, Stefan Rahlfs, Katja Becker Biological chemistry . 2002,第5期

机译：疟原虫恶性疟原虫的谷胱甘肽S-转移酶：潜在药物靶标的表征
4. Drug target interaction predictions using PU- Leaming under different experimental setting for four formulations namely known drug target pair prediction, drug prediction, target prediction and unknown drug target pair prediction [C] . Hetal Rahul Rajpura, Alioune Ngom IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology . 2018

机译：使用PU-Leaming在不同实验设置下针对四种制剂的药物靶相互作用预测，即已知药物靶对预测，药物预测，靶预测和未知药物靶对预测
5. Studies of Malarial Parasite Chloroquine Resistance Transporter and Kinase Proteins: Key Targets for Evolving Drug Therapies [D] . Hassett, Matthew Ryan. 2017

机译：疟原虫氯喹抗性转运蛋白和激酶蛋白的研究：不断发展的药物治疗的主要目标
6. Malarial parasite pathogenesis and drug targets [O] . Paul D Roepe 2009

机译：疟原虫的发病机理和药物靶标
7. Malarial parasite pathogenesis and drug targets [O] . Roepe, Paul D 2009

机译：疟原虫的发病机理和药物靶标
8. Comparative Drug Response of Sensitive and Resistant Strains of Malarial Parasites Using In Vitro Bioassays and Animal Models [R] . Gupta, C. M. , Kamboj, V. P. 1998

机译：使用体外生物测定和动物模型比较敏感和抗性疟疾寄生虫株的药物反应

Drugs and Drug Targets Against the Malarial Parasites

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