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Constructing “High-Risk Women”: The Development and Standardization of a Breast Cancer Risk Assessment Tool

机译：构建“高风险妇女”：乳腺癌风险评估工具的开发和标准化

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摘要

Recently, two prescription drugs (tamoxifen and raloxifene) have become salient to breast cancer prevention. With the advent of these drugs, referred to as “chemoprevention,” a mandate has emerged to classify certain women as high risk for breast cancer to determine a group of legitimate users of the drugs. This article examines the development and standardization of the model used to create such a group of high-risk women. The author argues that while the model remains uncertain and controversial, it has become the standard tool for the many jobs associated with legitimizing chemoprevention use in the United States. It has become the assumed standard—shaping practices, identities, and definitions—through its organizational embeddedness in the multiple practices and public images of chemoprevention despite its uncertainty and widespread critique.
机译：最近，两种处方药（他莫昔芬和雷洛昔芬）已成为预防乳腺癌的重要方法。随着被称为“化学预防”的这些药物的出现，一项授权将某些妇女归为罹患乳腺癌的高风险，从而确定了该类药物的合法使用者。本文研究了用于创建这类高风险女性群体的模型的开发和标准化。作者认为，尽管该模型仍然不确定且有争议，但它已成为美国合法使用化学预防剂相关的许多工作的标准工具。尽管它具有不确定性和广泛的批评性，但由于其在化学预防的多种实践和公众形象中的组织嵌入性，它已成为公认的标准-塑造实践，身份和定义。

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