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首页> 外文期刊>The Science of the Total Environment >Interactions between climate factors and air pollution on daily HFMD cases: A time series study in Guangdong, China
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Interactions between climate factors and air pollution on daily HFMD cases: A time series study in Guangdong, China

机译：日常手足口病病例中气候因素与空气污染之间的相互作用：中国广东的时间序列研究

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Background: Prior studies have shown that climate factors and air pollution are associated with hand, foot, and mouth disease (HFMD) epidemics. However, the interaction between air pollution and climate factors remains unknown.Methods: Daily HFMD counts from2009 through 2012 in Guangdongwere collected. We used distributed lag non-linear models to assess the associations of climate factors and air pollution on HFMD cases. The effects of climate factors were stratified by air pollution stratum to examine the interaction effect of air quality index (AQI) and temperature, as well as relative humidity. In addition, we explored the variability across gender groups.Results: We observed associations between HFMD cases and environmental factors, including temperature, relative humidity, and AQI. The highest relative risks (RR) were observed at themiddle level of temperature and AQI, and high level of relative humidity. The effects for the interaction between AQI and climate factors on HFMD cases were also statistically observed. Compared with low level temperatures (= 23.5 degrees C), high level temperatures (= 23.5 degrees C) had a RR of 1.486 (95% CI: 1.469,1.503) on days with "good"air quality (AQI = 46), and RR of 1.013 (95% CI: 1.003,1.023) on days with "moderate" air quality (AQI 46). For relative humidity, the high level (77%) had a RR of 1.082 (95% CI: 1.076,1.089) on days with "good"air quality, and RR of 1.039 (95% CI: 1.033,1.046) on days with "moderate" air quality. The associations and the interactions remained robust for males and females.Conclusions: Our findings indicate that climate factors and air pollution imposed lagged and non-linear effects on HFMD epidemics. The effects of climate factors on health potentially vary by AQI. Our study is practical and useful for targeted prevention and control, and provides environmental-based evidence. (c) 2018 Elsevier B.V. All rights reserved.
机译：背景：先前的研究表明，气候因素和空气污染与手足口病（HFMD）的流行有关。方法：收集广东省2009年至2012年的手足口病日数。我们使用分布式滞后非线性模型来评估手足口病病例中的气候因素与空气污染之间的关联。通过空气污染层对气候因素的影响进行分层，以检验空气质量指数（AQI）与温度以及相对湿度的相互作用。此外，我们还研究了性别群体之间的差异。结果：我们观察到手足口病病例与环境因素之间的关联，包括温度，相对湿度和AQI。在中等水平的温度和AQI以及较高的相对湿度下，观察到最高相对风险（RR）。还统计地观察了AQI和气候因素之间的相互作用对手足口病的影响。与低水平温度（<= 23.5摄氏度）相比，高水平温度（> = 23.5摄氏度）在空气质量为“好”的情况下的RR为1.486（95％CI：1.469,1.503）（AQI < = 46），并且在空气质量为“中等”（AQI> 46）的情况下，RR为1.013（95％CI：1.003,1.023）。对于相对湿度，高水平（> 77％）的空气质量为“好”时的RR为1.082（95％CI：1.076,1.089），RR为1.039（95％CI：1.033,1.046）在空气质量为“中等”的日子。结论：我们的发现表明，气候因素和空气污染对手足口病的流行产生滞后和非线性影响。气候因素对健康的影响可能因AQI而异。我们的研究对于有针对性的预防和控制是实用且有用的，并提供了基于环境的证据。 （c）2018 Elsevier B.V.保留所有权利。

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