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首页> 外文期刊>The Science of the Total Environment >Comprehensive toxicological study over 160 processing factors of pesticides in selected fruit and vegetables after water, mechanical and thermal processing treatments and their application to human health risk assessment
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Comprehensive toxicological study over 160 processing factors of pesticides in selected fruit and vegetables after water, mechanical and thermal processing treatments and their application to human health risk assessment

机译：经过水，机械和热加工处理的特定水果和蔬菜中160种农药加工因子的综合毒理学研究及其在人体健康风险评估中的应用

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The challenge of the present comprehensive toxicological study was to evaluate water, mechanical and thermal processing factors (PFs) of twenty four pesticides (acetamiprid, alpha-cypermethrin, azoxystrobin, boscalid, bupyrimate, chlorpyrifos, chlorothalonil, cyprodinil, deltamethrin, difenoconazole, fenazaquin, fenhexamid, fludioxonil, folpet, iprodione, lambda-cyhlothrin, metalaxyl, pirymicarb, propargite, pyraclostrobin, tetraconazole, tiophanate methyl, thiram, trifloxystrobin) in different fruit and vegetables and estimate health risk for adults and children. The water (PF = 0,09-0,94), mechanical (PF = 0,13-0,32) and thermal (PF = 0,02-0,57) technology significantly or completely reduced concentrations of twenty one active substances in broccoli, tomatoes, strawberries and black currants. Pyrethroid insecticides (alpha-cypermethrin, deltamethrin and lambda-cyhalothrin) exhibited PF above one in berries influenced by high temperatures. Comprehensive processing factor database technology/pesticide/matrix (over 160 PFs) for 24 pesticides in selected fruit and vegetable species after different processing treatments was created. This paper for the first time compares health risk assessments of acute and chronic of two subpopulations of adults and the most critical group of small children using two mathematical models, without (I) and with including (II) calculated PF values. More realistic estimation of the dietary intakes of the pesticides was achieved using PFs. The hazard quotients (HQs) estimated from chronic and acute dietary exposure (Model l) were above 20% and after intake correction (Model II) were reduced to HQs = 11.5% after water, 3% mechanical and 9.5% thermal treatment. Published by Elsevier B.V.
机译：目前的综合毒理学研究面临的挑战是评估二十四种农药（对乙酰氨基酚，α-氯氰菊酯，嘧菌酯，boscalid，丁草酸，毒死rif，百菌清，扑热息痛，溴氰菊酯，苯乙康唑，芬太尼，在不同的水果和蔬菜中使用苯甲酰胺，氟地西尼，氟哌啶，异丙洛酮，lambda-氯氟氰菊酯，甲霜灵，吡虫威，丙炔，吡咯菌酯，四康唑，噻吩甲酸酯，噻菌胺，三氟杀螨醇），并估计成人和儿童的健康风险。水（PF = 0,09-0,94），机械（PF = 0,13-0,32）和热（PF = 0,02-0,57）技术显着或完全降低了二十一种活性物质的浓度在西兰花，西红柿，草莓和黑加仑中。拟除虫菊酯类杀虫剂（α-氯氰菊酯，溴氰菊酯和lambda-氯氟氰菊酯）在受高温影响的浆果中的PF值高于1。创建了经过不同加工处理后的特定水果和蔬菜物种中24种农药的综合加工因子数据库技术/农药/基质（160 PFs以上）。本文首次使用两种数学模型（不包括（I）且包括（II）计算出的PF值）比较了两个成年人口和最关键的小儿童群体的急性和慢性健康风险评估。使用PFs可以更实际地估算农药的饮食摄入量。根据慢性和急性饮食暴露（模型1）估算的危险商（HQs）高于20％，并且在进水校正（3％机械处理和9.5％热处理）后，校正摄入量（模型II）降至HQs = 11.5％。由Elsevier B.V.发布

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