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首页> 外文期刊>The Science of the Total Environment >Impacts of exposure to humidex on the risk of childhood asthma hospitalizations in Hefei, China: Effect modification by gender and age
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Impacts of exposure to humidex on the risk of childhood asthma hospitalizations in Hefei, China: Effect modification by gender and age

机译：中国合肥市暴露于加湿剂对儿童哮喘住院风险的影响：性别和年龄的影响修正

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Background: With global climate change, there is growing concern about the effects of temperature changes on childhood asthma. However, current research only focuses on the effects of temperature, while ignoring the adverse effects of humidity on children.Objectives: Our study aimed to quantify the impact of humidex on childhood asthma hospitalizations, which combined temperature and humidity, and further to assess how the effect is modified by individual-factors, such as age and gender.Methods: Poisson generalized linear models combined with distributed lag nonlinear models were used to estimate the association between daily childhood asthma hospitalizations and humidex from 2013 to 2016. Air pollutions (CO, O-3, and NO2) and wind velocity were modelled simultaneously using DLNM, as well as day of week, seasonality and long-term trend.Results: Low humidex was associated with an increased risk of admissions for asthma in children. The adverse effect appeared on the 4th day, with the RR of 1.045 (95% CI: 1.007-1.084) and lasted until the 7th day (RR: 1.045, 95%CI: 1.006-1.085). Compared with the male, there was an immediate effect on female exposed to low humidex. And the female seems to be more sensitive to low humidex. Besides, the significant effects of humidex on children asthma were detected in the children with preschool and school-age, whereas not for the subgroup of infants. And the school-age children are most sensitive to low humidex.Conclusions: Low humidex was associated with the increased risk of admissions for childhood asthma in Hefei. Children suffering from asthma should avoid exposure to the low humidex environment, especially in female and school-age children. In addition, the index of humidex was more significant for disease prevention and public health than the average temperature. These findings may provide epidemiology evidence for formulating precaution guidelines to reduce the risk of childhood asthma hospitalizations. (c) 2019 Elsevier B.V. All rights reserved.
机译：背景：随着全球气候变化，人们越来越关注温度变化对儿童哮喘的影响。然而，当前的研究仅关注温度的影响，而忽略了湿度对儿童的不利影响。目的：我们的研究旨在量化加湿剂对温度和湿度结合的儿童哮喘住院的影响，并进一步评估方法：采用泊松广义线性模型与分布滞后非线性模型相结合，估算了2013年至2016年儿童哮喘住院日和加湿量之间的关联。空气污染（CO，O -3和NO2）和风速同时使用DLNM以及星期几，季节性和长期趋势进行建模。结果：低湿润与儿童哮喘发作风险增加相关。不良反应在第4天出现，RR为1.045（95％CI：1.007-1.084），并持续到第7天（RR：1.045，95％CI：1.006-1.085）。与男性相比，暴露于低湿润的女性具有立竿见影的效果。而且女性似乎对低湿润更敏感。此外，在学龄前和学龄儿童中发现了加湿剂对儿童哮喘的显着影响，而在婴儿亚组中则没有。结论：合肥市儿童潮气吸入率偏低与儿童入院风险增加有关。患有哮喘的儿童应避免暴露于低湿润环境中，尤其是在女性和学龄儿童中。此外，对于疾病预防和公共卫生，湿度指数比平均温度更为重要。这些发现可能为制定预防指导方针以减少儿童哮喘住院风险的流行病学证据提供依据。 （c）2019 Elsevier B.V.保留所有权利。

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