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首页> 外文期刊>The Science of the Total Environment >Long-term exposure to ambient fine particulate matter and fasting blood glucose level in a Chinese elderly cohort
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Long-term exposure to ambient fine particulate matter and fasting blood glucose level in a Chinese elderly cohort

机译：长期接触中国老年人群的环境细颗粒物和空腹血糖水平

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摘要

Fasting blood glucose level is the primary indicator for the diagnosis of diabetes. We aim to conduct a longitudinal study on the association between long-term fine particulate matter (PM_(2.5)) exposure and fasting blood glucose concentrations. We recruited and followed up 1449 participants older than 65 years of age in 2009, 2012, 2014, and 2017 in eight counties in China. Fasting blood glucose was repeatedly measured 3697 times in total among these participants. Data on annual ground-level PM_(2.5) concentrations with a 0.01° spatial resolution from 2005 to 2016 were used to assess exposures. An increase of 10 μg/m~3 in 3-year average exposure to PM_(2.5) was associated with an increase of 0.146 mmol/L (95% confidence interval [CI]: 0.045,0.248) in fasting blood glucose in all participants. The association was more pronounced among the subgroup with diabetes compared to the subgroup without diabetes (P< .05). In conclusion. Long-term PM_(2.5) exposure was associated with an increase in fasting blood glucose levels among elderly people. Elderly individuals with diabetes are particularly vulnerable to high level exposures of PM_(2.5). Summary: Long-term PM_(2.5) exposure was associated with an increase in fasting blood glucose levels among elderly people. Elderly individuals with diabetes are particularly vulnerable to high level exposures of PM_(2.5).
机译：空腹血糖水平是诊断糖尿病的主要指标。我们旨在对长期的细颗粒物（PM_（2.5））暴露与空腹血糖浓度之间的关系进行纵向研究。我们在2009年，2012年，2014年和2017年在中国的8个县招募并跟踪了1449名65岁以上的参与者。在这些参与者中，空腹血糖总共被重复测量了3697次。使用2005年至2016年空间分辨率为0.01°的年度地面PM_（2.5）浓度数据评估暴露量。所有参与者的3年平均PM_（2.5）暴露量增加10μg/ m〜3与空腹血糖升高0.146 mmol / L（95％置信区间[CI]：0.045,0.248）相关。与没有糖尿病的亚组相比，患有糖尿病的亚组之间的关联更为明显（P <.05）。结论。长期PM_（2.5）暴露与老年人空腹血糖水平升高有关。老年糖尿病患者尤其容易受到PM_（2.5）的高水平暴露。摘要：长期PM_（2.5）暴露与老年人空腹血糖水平升高有关。老年糖尿病患者尤其容易受到PM_（2.5）的高水平暴露。

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