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Response to Gottesfeld and Jacobs 2016

机译:回应Gottesfeld和Jacobs 2016

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We are grateful for the evaluation and insights into our recently published article on lead in public playground paints (Turner et al., 2016) by Gottesfeld and Jacobs (2016-in this issue), and are pleased that the authors are in broad agreement with the findings and their implications. Gottesfeld and Jacobs (2016-in this issue), however, raise an important issue that was addressed by Turner et al. (2016) as an area of contention; namely, the consideration and evaluation of oral bioaccessibility of Pb (and chromium) in paints. We used a simple, operational means of evaluating bioaccessibility to children by exposing ground paint samples to a mixture of pepsin in dilute HC1 at 37 ℃, a common component of many physiologically-based extraction techniques (Hamel et al., 1999; Ibanez et al., 2010). The results are informative in demonstrating that bioaccessibility in the digestive tract, and as a percentage of total Pb, ranged from less than 0.1 to about 17, and that Pb in coloured paints and that contain chromate is less accessible than lead in white paints that do not contain chromate. Such information is also useful in providing comparisons of Pb bioaccessibility in exterior playground paints with similar measures of accessibility in a variety of other environmental solids, including house dusts (Turner and Simmonds, 2006), soils (Hamel et al., 1999), boat paints (Turner and Radford, 2010) and road dusts (Elom et al., 2014).
机译:我们感谢Gottesfeld和Jacobs(2016-本期)最近发表的有关公共操场涂料中铅的文章(Turner等人,2016)的评估和见解,并很高兴与作者达成广泛共识调查结果及其含义。 Gottesfeld和Jacobs(2016年,本期)提出了一个重要的问题,特纳(Turner)等人解决了这个问题。 (2016)作为争论的领域;即考虑和评估涂料中铅(和铬)的口服生物可及性。我们使用一种简单的,可操作的方法来评估儿童的生物可及性,方法是将地面涂料样品暴露于37℃稀盐酸中的胃蛋白酶混合物中,这是许多基于生理的提取技术的共同组成部分(Hamel等,1999; Ibanez等。 (2010年)。结果表明,消化道中的生物可及性(占总Pb的百分比)范围从小于0.1到约17,并且有色涂料中含有铬酸盐的Pb比白色涂料中的铅更难获得。不含铬酸盐。此类信息还可用于比较室外游乐场涂料中的Pb生物可及性,以及在其他各种环境固体中(包括房屋尘土(Turner和Simmonds,2006年),土壤(Hamel等人,1999年),船等)对可及性的相似测量。油漆(特纳和拉德福,2010年)和道路扬尘(Elom等人,2014年)。

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