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Inactivation of vegetative bacterial threat agents on environmental surfaces

机译:在环境表面上灭活植物细菌威胁因子

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摘要

Following a wide-area biological terror attack, numerous decontamination technologies, techniques, and strategies will be required for rapid remediation. Establishing an understanding of how disinfectants will perform under field conditions is of critical importance. The purpose of this study was to determine the efficacy of several liquid decontaminants, when used to inactivate vegetative biological agents on environmental surfaces. Aluminum, carpet, concrete, glass, and wood coupons were inoculated with 1 × 10~8 CFU of Burkholderia mallei, Francisella tularensis. Vibrio cholerae, or Yersinia pestis. Using spray-based application methods, decontamination was then attempted with pH-adjusted bleach, 1% citric acid, 70% ethanol, quaternary ammonia, or Pine-Sol~?. Results indicated that decontamination efficacy varied significantly by decontaminant and organism. Materials such as wood are difficult to decontaminate, even when using sporicides. The data presented here will help responders develop efficacious remediation strategies following a large-scale contamination incident.
机译:在发生大范围的生物恐怖袭击之后,将需要多种净化技术,技术和策略来进行快速补救。建立对消毒剂在野外条件下的性能的理解至关重要。这项研究的目的是确定几种液体去污剂用于灭活环境表面上的植物性生物制剂时的功效。用1×10〜8 CFU的Burkholderia mallei,Francisella tularensis接种铝,地毯,混凝土,玻璃和木材试样。霍乱弧菌或鼠疫耶尔森氏菌。然后使用基于喷雾的施用方法,尝试使用经pH调节的漂白剂,1%柠檬酸,70%乙醇,季铵盐或Pine-Sol®进行净化。结果表明,去污效果因去污剂和生物体而异。即使使用杀虫剂,木材等材料也难以去污。此处提供的数据将帮助响应者在大规模污染事件发生后制定有效的补救策略。

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