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Occupational exposure to whole body vibrations and birth outcomes -A nationwide cohort study of Swedish women

机译：职业接触全身振动和出生结果 - 瑞典女性的全国队列研究

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摘要

Background: More women in reproductive ages are entering occupations where exposure to whole body vibrations (WBV) is common (e.g. in transportation and construction). Previous studies based on self-assessed exposure suggest increased risks of adverse birth outcomes, but it is unclear at what exposure levels and if the current exposure guidelines are appropriate during pregnancy. Objectives: To investigate whether occupational WBV-exposure increases the risk of preterm birth, low birth weight, and/or small-for-gestational age, in a large, nationwide, prospective, cohort study. Design: The Fetal Air Pollution Exposure cohort (FAIR) was formed by merging data from multiple, national registers, and the present study includes singletons born 1994-2014 to working women in Sweden (n = 1,091,080 births). WBV-exposure was assessed quantitatively using a job-exposure matrix based on measurements, and calculated odds ratios were adjusted for potential confounders such as smoking and BM1, and other occupational exposures like noise, combustion particles, and physically and psychologically strenuous work. Data on absence from work (full-/part time, sick leave, parental leave, etc.) was also used. Results: Exposure to WBV during pregnancy, among women with low absence from work (n = 476,419), was associated with an increased risk of preterm birth, below the occupational exposure limit (1.15 m/s~2). Compared to unexposed mothers, the OR was 1.38 (95% CI: 1.05,1.83) for exposure ＞0.5 m/s~2, corresponding to an increase from 47/1000 cases to 65/1000 cases. No increased risk was found for small-for-gestational age. Conclusions: Exposure to WBV was associated with an increased risk of preterm birth. The results suggest that the current permissible exposure and action levels for WBV-exposure do not adequately protect pregnant women with continuous exposure.
机译：背景：繁殖年龄的更多女性正在进入职业，其中暴露于全身振动（WBV）是常见的（例如，在运输和建设中）。以前的自我评估曝光的研究表明增加了不良出生结果的风险，但在怀孕期间当前的暴露指南适当时，尚不清楚曝光率。目的：调查职业WBV暴露是否会增加早产，出生体重和/或小于胎龄的风险，在大型，全国范围内，前瞻性的队列研究中。设计：胎儿空气污染暴露队列（公平）是通过从多个，国家寄存器和本研究中融合的数据而形成的，包括1994 - 2014年的单身人士到瑞典的职业妇女（n = 1,091,080个诞生）。通过基于测量的效果矩阵来定量评估WBV-曝光，并根据诸如吸烟和BM1等潜在混淆来调整计算的优势比，以及其他职业暴露，如噪声，燃烧颗粒，身体和心理上剧烈的工作。还使用了关于工作（全/兼职，病假，父母假等）的数据。结果：暴露于妊娠期间的WBV，缺乏工作缺失的女性（n = 476,419）与早产的风险增加有关，低于职业暴露限制（1.15米/ s〜2）。与未曝光的母亲相比，或为1.38（95％CI：1.05,1.83），用于暴露> 0.5米/ s〜2，对应于47/1000例增加至65/1000例。没有对小胎龄的风险增加。结论：暴露于WBV与早产的风险增加有关。结果表明，WBV暴露的目前允许的暴露和动作水平不会充分保护孕妇持续暴露。

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  • 来源
    《The Science of the Total Environment》 |2021年第10期|141476.1-141476.11|共11页
  • 作者

    H. Skroeder; H. Pettersson; F. Norlen; P. Gustavsson; L. Rylander; M. Albin; J. Selander;

  • 作者单位

    Unit of Occupational Medicine Institute of Environmental Medicine Karolinska Institutet Box 210 SE-171 77 Stockholm Sweden;

    Occupational and Environmental Medicine Department of Public Health and Clinical Medicine Umea University SE-901 87 Umea Sweden;

    Unit of Occupational Medicine Institute of Environmental Medicine Karolinska Institutet Box 210 SE-171 77 Stockholm Sweden;

    Unit of Occupational Medicine Institute of Environmental Medicine Karolinska Institutet Box 210 SE-171 77 Stockholm Sweden;

    Division of Occupational and Environmental Medicine Institute of Laboratory Medicine Lund University Box 188 SE-221 85 Lund Sweden;

    Unit of Occupational Medicine Institute of Environmental Medicine Karolinska Institutet Box 210 SE-171 77 Stockholm Sweden;

    Unit of Occupational Medicine Institute of Environmental Medicine Karolinska Institutet Box 210 SE-171 77 Stockholm Sweden;

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  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    Work; Oscillation; Gestation; Fetal development; PTB; LBW; SGA;

    机译：工作;振荡;妊娠;胎儿发展;PTB;LBW;SGA.;

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