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Ultrafine particulate air pollution and pediatric emergency-department visits for main respiratory diseases in Shanghai, China

机译：超细颗粒气体污染和儿科应急部门参观上海主要呼吸系统疾病

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摘要

Background: Few studies have explored the short-term effects of ultrafine particles (UFPs, particles ＜ 0.1 μm) air pollution on the exacerbations of pediatric respiratory diseases. Objectives: We aimed to evaluate short-term association between UFP and emergency-department visits (EDVs) for main pediatric respiratory diseases. Methods: We collected daily data on UFP and pediatric EDVs for main respiratory diseases [asthma, pneumonia, bronchitis and upper respiratory tract infections (URTI) ] from 66 hospitals in Shanghai, China from 2016 to 2018. Generalized additive models combined with polynomial distributed lag models were applied to explore the associations between UFP level and pediatric EDVs for respiratory diseases. We fitted two-pollutant models with criteria air pollutants and performed stratified analyses by gender and age. Results: UFP was associated with increased EDVs for all respiratory diseases in cumulative lags up to 2 d and 3 d. The greatest risk was found at cumulative lags (0-2 d) for all respiratory diseases. At cumulative lags (0-2 d), an interquartile range increase in concentrations of UFP (1800 particles/cm3) was associated with relative risks of EDVs due to asthma 11.35,95% confidence interval (CI): 1.14-1.59], pneumonia (1.20,95% CI: 1.04-1.38), bronchitis (1.17,95% CI: 1.03-1.33) and URTI (1.14, 95% CI: 1.02-1.28). These associations were almost unchanged when controlling for criteria air pollutants, and there was no threshold below which the associations were not present. There were stronger associations in children aged 0-13 years.Conclusions: Short-term exposure to UFP may independently increase the risks of EDVs for asthma, pneumonia, bronchitis and URTI exacerbations among children.
机译：背景：少数研究探索了超细颗粒（UFP，颗粒<0.1μm）空气污染对儿科呼吸系统疾病的恶化的短期影响。目标：我们旨在评估紫外线和急诊部门访问（EDV）之间的短期关联，用于主要儿科呼吸道疾病。方法：从2016到2018年，我们从中国上海的66家医院收集了对主要呼吸系统疾病的每日数据和儿科EDV的每日数据，用于来自中国上海的66家医院，从中国上海的66家医院。广义添加剂模型与多项式分布式滞后相结合应用模型来探索UFP水平与呼吸疾病儿科EDV之间的关联。我们用两种污染模型，具有标准空气污染物，并通过性别和年龄进行分层分析。结果：UFP与累积滞后的所有呼吸系统疾病增加的EDV增加，高达2 D和3天。对于所有呼吸疾病，累积滞后（0-2d）发现了最大的风险。在累积滞后（0-2d）时，由于哮喘11.35,95％置信区间（CI）：1.14-1.59]，肺炎，肺炎，肺炎，患有UFP浓度（1800颗粒/ CM3）的浓度增加与EDV的相对风险相关联（1.20,95％CI：1.04-1.38），支气管炎（1.17,95％CI：1.03-1.33）和URTI（1.14,95％CI：1.02-1.28）。在控制标准空气污染物时，这些关联几乎保持不变，下面没有阈值，联想不存在。 50岁的儿童有更强的协会。结论：联合国的短期暴露可能独立地增加哮喘，肺炎，支气管炎和儿童荨麻治结果的EDV的风险。

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  • 来源
    《Science of the total environment》 |2021年第25期|145777.1-145777.6|共6页
  • 作者

    Hongjin Li; Xiaoling Li; Hongmei Zheng; Lijuan Liu; Yihan Wu; YufengZhou; Xia Meng; Jianguo Hong; Lanfang Cao; Yanming Lu; Xiaoyan Dong; Min Xia; Bo Ding; Liling Qian; Libo Wang; Wenhao Zhou; Yonghao Gui; Haidong Kan; Renjie Chen; Xiaobo Zhang;

  • 作者单位

    School of Public Health Key Lab of Public Health Safety of the Ministry of Education and NHC Key Laboratory of Health Technology Assessment Fudan University Shanghai 200032 China;

    Department of Respiratory Medicine Children's Hospital of Fudan University Shanghai 201102 China;

    Department of Respiratory Medicine Children's Hospital of Fudan University Shanghai 201102 China;

    Department of Respiratory Medicine Children's Hospital of Fudan University Shanghai 201102 China;

    School of Public Health Key Lab of Public Health Safety of the Ministry of Education and NHC Key Laboratory of Health Technology Assessment Fudan University Shanghai 200032 China;

    Institute of Pediatrics Children's Hospital of Fudan University Shanghai 201102 China Institutes of Biomedical Sciences Fudan University Shanghai 200032 China;

    School of Public Health Key Lab of Public Health Safety of the Ministry of Education and NHC Key Laboratory of Health Technology Assessment Fudan University Shanghai 200032 China;

    Department of Pediatrics. Shanghai General Hospital Shanghai Jiaotong University Shanghai 200080 China;

    Department of Pediatrics Renji Hospital Shanghai jiao Tong University Shanghai 200127 China;

    Department of Pediatrics South Campus Renji Hospital Shanghai Jiao Tong University Shanghai 201112 China;

    Department of Respiratory Medicine Children's Hospital of Shanghai Jiaotong University Shanghai 200040 China;

    Department of Pediatrics Renji Hospital Shanghai jiao Tong University Shanghai 200127 China;

    Department of Pediatrics South Campus Renji Hospital Shanghai Jiao Tong University Shanghai 201112 China;

    Department of Respiratory Medicine Children's Hospital of Fudan University Shanghai 201102 China;

    Department of Respiratory Medicine Children's Hospital of Fudan University Shanghai 201102 China;

    Department of Neonatology Children's Hospital of Fudan University Shanghai 201102 China;

    Cardiovascular Center Children's Hospital of Fudan University Shanghai 201102 China;

    School of Public Health Key Lab of Public Health Safety of the Ministry of Education and NHC Key Laboratory of Health Technology Assessment Fudan University Shanghai 200032 China;

    School of Public Health Key Lab of Public Health Safety of the Ministry of Education and NHC Key Laboratory of Health Technology Assessment Fudan University Shanghai 200032 China;

    Department of Respiratory Medicine Children's Hospital of Fudan University Shanghai 201102 China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Ultrafine particle; Respiratory diseases; Air pollution; Time-series study;

    机译：超细颗粒;呼吸疾病;空气污染;时间序列研究;

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