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Why is your right arm as long as your left? How does your heart grow just big enough to fit inside your chest, and not larger? Why is your head "smaller" in proportion to your body size now than when you were a baby? The question of how animal growth and size are regulated and coordinated has fascinated generations of biologists. However, the underlying mechanisms still remain unclear. In recent years, the power and versatility of Drosophila genetics, combined with some imaginative experiments by fruit fly researchers, have revealed new ideas about the control of animal growth. In particular, several recent reports using this model system have shown how organ-to-organ signaling can influence both the rate of Drosophila body growth and final organ size. These findings may provide clues about human growth as well.
机译:为什么右臂和左臂一样长?您的心脏如何长到足以容纳您的胸部而又不能容纳得更大?为什么现在的头部比婴儿时的头部小一些?如何调节和协调动物生长和大小的问题已经引起了几代生物学家的关注。但是,基本机制仍然不清楚。近年来,果蝇遗传学的力量和多功能性,再加上果蝇研究人员的一些富有想象力的实验,揭示了关于控制动物生长的新思路。特别是,最近使用此模型系统的几份报告显示器官间信号传导如何影响果蝇身体生长速率和最终器官大小。这些发现也可能提供有关人类成长的线索。

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  • 来源
    《The Scientist》 |2013年第3期|45-49|共5页
  • 作者

    SAVRAJ S. GREWAL;

  • 作者单位

    Clark H. Smith Brain Tumour Centre,at the University of Calgary, Alberta;

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  • 正文语种 eng
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