Academic Medicine to the Rescue

J. Lynn Rutkowski; Giora Z. Feuerstein

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Academic Medicine to the Rescue

机译：抢救学术医学

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The rate of discovery and approval of new medicines is declining despite substantially increased investment. Safety and efficacy failures are caused by:rn1. Highly novel targets, for which there is limited knowledge of the biology and role in human diseasern2. Diseases that are poorly understood in terms of patho-physiologic mechanisms, such as chronic obstructive pulmonary disease, osteoarthritis, and Alzheimer's diseasern3. Limitations in the animal models of human diseasern4. Limited biomarkers to optimize treatmentrnThe pharmaceutical industry is preeminent in moving compounds from discovery through the development phases. It's scientific and technological expertise is phenomenal - from molecular modeling to protein engineering to metabolic pathways for compounds/biologies - all are industry proficiencies.

机译：尽管投入大量资金，新药的发现和批准率却在下降。安全性和有效性失败是由于：rn1。高度新颖的靶标，对其生物学和在人类疾病中的作用的了解有限。在病理生理机制方面知之甚少的疾病，例如慢性阻塞性肺疾病，骨关节炎和阿尔茨海默氏病3。人类疾病动物模型的局限性4。有限的生物标记物可优化治疗方法制药行业在将化合物从发现转移到开发阶段方面具有举足轻重的地位。它的科学技术专长非凡，从分子建模到蛋白质工程再到化合物/生物的代谢途径，全都是行业精通。

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《Scientist》 |2008年第6期|28|共1页
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J. Lynn Rutkowski; Giora Z. Feuerstein;
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机译：天然抗Gal抗体作为敌人在医学Uri Galili博士学位，学术出版社（欧米尔的印记），伦敦，2018年。第1-300页。价格为95.50美元。天然抗Gal抗体作为敌人在医学中转过身的朋友，天然抗Gal抗体作为敌人的敌人在医学Uri Galili Uri Uri Uri uri Galili Galili博士学位，学术出版社学术出版社（互联网版印记），伦敦伦敦，2018年2018年。 PP。1 1 - 300 300。价格为95.50美元。
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5. Study of Women Faculty Members' Pursuit of Non-traditional Leadership Commitments Within Academic Medicine, Highlighting The Experiences of Women Faculty Members Enrolled In The Hedwig van Ameringen Executive Leadership Program for Women in Academic MedicineRTM. [D] . Simmons, Sharon. 2015

机译：研究女教师在学术医学领域对非传统领导力的追求，重点介绍了参加Hedwig van Ameringen学术医学女性行政领导者计划的女教师的经历。
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7. Academic medicine: who is it for?: Five rescue remedies for academic medicine [O] . House, William, Peters, David 2005

机译：学术医学：它是为谁准备的？：学术医学的五种补救措施

Academic Medicine to the Rescue

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