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Honeybee Sequencing: One Honey of an Idea

机译:蜜蜂测序:一个想法的蜂蜜

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In late May, the National Human Genome Research Institute (NHGRI) released its priority list of organisms under consideration for entry into the sequencing pipeline: One was the honeybee. It was a move that has numerous supporters. "We feel that sequencing [the bee] ... will provide important tools and unique models for a variety of different areas of biology, including social behavior," says Gene E. Robinson, professor of entomology and director of the neuroscience program at University of Illinois at Urbana-Champaign, and lead author of the proposal that the NHGRI reviewed. Robinson ticks off numerous reasons why the honeybee fits the institute's sequencing requirements: Bees are models for learning and memory; for studies of allergic disease; for gerontology research, as the long-lived, egg-producing queen is genetically identical to the much shorter-lived female workers; for studies of venom toxicology; and for studies of infectious diseases in dense societies. "The basic thrust that underlies everything about the [honeybee] genome is the notion [that], although phylogeneti-cally distant from the human, honeybees live in societies that rival our own in complexity and in success in dealing with the many challenges posed by social life," says Robinson. "They are literally a magic well for discoveries in biology in a huge range of biological disciplines," explains Francis Ratnieks, director of the Laboratory of Apiculture and Social Insects, University of Sheffield, UK. "If you study it, you could be studying practically any topic in biology."
机译:5月下旬,美国国家人类基因组研究所(NHGRI)发布了其正在考虑进入测序流程的生物的优先列表:一种是蜜蜂。此举得到了众多支持者的支持。 “我们认为,[蜜蜂]的测序……将为包括社会行为在内的各种不同生物学领域提供重要的工具和独特的模型,”昆虫学教授,大学神经科学计划主任Gene E. Robinson说。是厄本那-香槟分校伊利诺伊州分校的书目,也是NHGRI审核该提案的主要作者。罗宾逊(Robinson)提出了蜜蜂符合研究所测序要求的众多原因:蜜蜂是学习和记忆的模型;蜜蜂是学习和记忆的模型。用于过敏性疾病的研究;对于老年病学研究来说,长寿的产卵女王在基因上与寿命短得多的女工相同。用于毒液毒理学研究;并用于密集社会中的传染病研究。 “构成[蜜蜂]基因组一切基础的基本推论是[虽然]系统发育与人类距离遥远,但蜜蜂生活在与我们自己相比复杂的社会中,在应对挑战所带来的许多挑战方面,我们的成功社会生活。”鲁滨逊说。英国谢菲尔德大学养蜂学和社会昆虫实验室主任弗朗西斯·拉特尼克斯解释说:“从字面上看,它们是在众多生物学学科中发现生物学的神奇之地。” “如果您研究它,您几乎可以研究生物学的任何主题。”

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