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首页> 外文期刊>Sensors and Actuators. B, Chemical >Surface-enhanced Raman scattering detection of chemical and biological agents using a portable Raman integrated tunable sensor
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Surface-enhanced Raman scattering detection of chemical and biological agents using a portable Raman integrated tunable sensor

机译：使用便携式拉曼集成可调传感器对化学和生物制剂进行表面增强拉曼散射检测

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摘要

This paper describes a compact and rugged Raman integrated tunable sensor coupled with surface-enhanced Raman scattering substrates for the screening of a wide variety of chemical and biological agents for homeland defense applications. The field-deployable instrument, consisting of an 830-nm diode laser for excitation and an avalanche photodiode (APD) for detection, is a fully integrated, tunable, "point-and-shoot" Raman device based on solid-state acousto-optic tunable filter (AOTF) technology. It can provide direct identification of chemical and biological samples in a few seconds under field conditions. This paper illustrates some applications of this portable device for the detection of various compounds of particular interest for homeland defense applications. These include methyl parathion (a nerve agent simulant) and dipicolinic acid (a biomarker for bacillus endospore), and other chemical warfare simulants such as dimethyl methylphosphonate, pinacolyl methylphosphonate, diethyl phosphoramidate, and 2-chloroethyl ethylsulfide, which are simulants for sarin (GB), soman (GD), tabun (GA), and sulfur mustard (HD), respectively, and intact bacteria such as Bacillus globigii, Erwinia herbicola, and Bacillus thuringiensis, which are simulants for biological warfare agents.
机译：本文介绍了一种紧凑而坚固的拉曼集成可调传感器，结合了表面增强的拉曼散射基板，可用于筛选用于国土防御应用的多种化学和生物制剂。可现场部署的仪器由用于激发的830 nm二极管激光器和用于检测的雪崩光电二极管（APD）组成，是基于固态声光的完全集成的，可调的“傻瓜式”拉曼器件。可调滤波器（AOTF）技术。它可以在野外条件下在几秒钟内直接识别化学和生物样品。本文说明了该便携式设备在检测国土防御应用中特别感兴趣的各种化合物方面的一些应用。其中包括甲基对硫磷（一种神经毒物模拟物）和二吡啶甲酸（一种内生芽孢杆菌的生物标记物），以及其他化学战模拟物，例如甲基膦酸二甲酯，频哪醇甲基膦酸酯，氨基磷酸二乙酯和2-氯乙基乙基硫化物，它们是沙林的模拟物（GB ），梭曼（GD），塔布恩（GA）和硫芥子（HD）以及完整的细菌，例如globigii芽孢杆菌，草食欧文氏杆菌和苏云金芽孢杆菌，它们是生物战剂的模拟物。

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