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首页> 外文期刊>IEEE sensors journal >An Integrated Amplifier With Passive Neutralization of Myoelectric Interference From Neural Recording Tripoles
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An Integrated Amplifier With Passive Neutralization of Myoelectric Interference From Neural Recording Tripoles

机译：集成式放大器，可中和神经记录三极管产生的肌电干扰。

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This paper describes an integrated amplifier for neural recording from tripolar electrode books connected in the quasi-tripole arrangement. The same tripole is used in the implant for neural stimulation. To remove myoelectric interference from neural recordings, a resistor–capacitor network is used to balance the electrode impedances in the tripole. The amplifier is programmable (recording mode, passband, gain, and trimming impedance) via a serial peripheral interface. Its front-end instrumentation amplifier employs current feedback to achieve high common-mode rejection ratio. The circuit was implemented in 0.35- $mu{rm m}$ CMOS technology and occupies an area of ${sim}{rm 1.2}~{rm mm}^{2}$. In the very-low noise mode, the analog front-end features a maximum of 0.68 $mu{rm V}_{rm rms}$ input-referred noise in the passband and consumes ${sim}{rm 310}~mu{rm A}$ from a 3 V supply. The measured common-mode rejection ratio of the instrumentation amplifier $({rm CMRR}_{rm IA})$ approaches 100 dB. The effect of component mismatch on the ${rm CMRR}_{rm IA}$ and the noise performance of the instrumentation amplifier are examined. In addition, the recording tripole is analyzed to derive the overall common-mode rejection ratio that is shown to exceed 80 dB. The ability of the neural amplifier to reduce myoelectric interference is demonstrated. The amplifier is also tested with a tripole immersed in saline in the stimulate-record mode.
机译：本文介绍了一种集成放大器，用于从以准三极布置方式连接的三极电极簿进行神经记录。植入物中使用相同的三脚架进行神经刺激。为了消除神经记录中的肌电干扰，电阻-电容网络用于平衡三脚架中的电极阻抗。该放大器可通过串行外设接口进行编程（记录模式，通带，增益和微调阻抗）。它的前端仪表放大器利用电流反馈来实现高共模抑制比。该电路以0.35- $ mu {rm m} $ CMOS技术实现，占用 $ {sim} {rm 1.2}〜{rm mm} ^ {2} $ 。在极低噪声模式下，模拟前端的最大最大值为0.68 $ mu {rm V} _ {rm rms} $ 在通带中为输入参考的噪声，并消耗 $ {sim} {rm 310}〜mu {rm A} $ 来自3 V电源。仪表放大器 $（{rm CMRR} _ {rm IA}）$ 的测量共模抑制比接近100 D b。组件不匹配对 $ {rm CMRR} _ {rm IA} $ 的影响以及仪表放大器的噪声性能被检查。另外，分析记录三极管以得出整体共模抑制比，该比显示为超过80 dB。证明了神经放大器减少肌电干扰的能力。放大器还用三极管在刺激记录模式下浸入盐水中进行了测试。

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