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首页> 外文期刊>IEEE sensors journal >Ocular Biometric Measurements to Diagnose Neurological Disorders Due to Wilson Disease
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Ocular Biometric Measurements to Diagnose Neurological Disorders Due to Wilson Disease

机译：眼生物计量学测量诊断由威尔逊病引起的神经系统疾病

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Wilson disease is a pathology because of a gene mutation causing malfunction in the copper excretion from the organism. Therefore, copper accumulation in the body gives rise to oxidative processes. Hence, this rare disease causes several disorders affecting tissues and organs. Neurological disorders lead to copper accumulation in the brain. Approximately 95% of individuals with neurological/psychiatric disorders show a visible symptom in their eyes known as Kayser-Fleischer ring. It is a golden-brown, sometimes orange or greyish, ring because of copper deposit in the cornea. In the medical screening, it is considered as a diagnostic sign of Wilson disease more than ever in individuals with neurological problems. The authors propose an innovative technique based on ocular biometric measurements to diagnose the pathology and the origin of a neurological disorder. An image processing algorithm detects the Kayser-Fleischer ring in the eye cornea through segmentation. Subsequently, biometric measurements provide further information on the severity level of pathology. The aim is to provide a non-invasive diagnostic technique to improve the accuracy of the current methods used in practice and to reduce the possible interpretation errors.
机译：威尔逊病是一种病理学，因为基因突变导致了生物体铜排泄的功能异常。因此，体内铜的积累引起氧化过程。因此，这种罕见的疾病引起影响组织和器官的几种疾病。神经系统疾病会导致铜在大脑中积聚。约有95％的神经系统/精神疾病患者的眼睛出现可见的症状，称为Kayser-Fleischer环。它是金棕色的，有时是橙色或灰色的环，因为角膜中有铜沉积。在医学筛查中，对于神经系统疾病患者，它被认为是威尔逊病的诊断指标。作者提出了一种基于眼部生物特征测量技术的创新技术，以诊断神经系统疾病的病理学和起源。图像处理算法通过分割来检测眼角膜中的Kayser-Fleischer环。随后，生物统计学测量提供了有关病理严重程度的更多信息。目的是提供一种非侵入性诊断技术，以提高实践中使用的当前方法的准确性并减少可能的解释错误。

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