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Novel Design of an Optical Probe for Detecting Perfusion Changes in Buccal Tissue

机译:用于检测颊组织灌注变化的光学探针的新颖设计

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Measuring the blood perfusion and microcirculation at a specific depth in human tissue is an important method to monitor oxygenation in critically ill patients. The optical probes, that are currently available in the market, are not capable of monitoring the blood perfusion from a given tissue layer and at a specific depth. We have designed a novel optical probe which is able to focus the light at a specific depth of ~670×μm in buccal tissue. The new probe consists of two light guides for sending and detecting the reflected light from the sampling area (tissue), and a lens to focus the light into the desired depth of the tissue and collect it back from the same area. The new optical probe has been compared to a commercial laser Doppler probe by collecting data from the same sampling area. The result from our probe showed 15% higher accuracy in detecting changes in blood perfusion compared with an existing commercial probe.
机译:测量人体组织特定深度的血液灌注和微循环是监测重症患者氧合的重要方法。当前在市场上可买到的光学探针不能监测来自给定组织层和特定深度的血液灌注。我们设计了一种新颖的光学探头,该探头能够将光聚焦在颊组织中约670×μm的特定深度。新型探头包括两个光导,用于发送和检测来自采样区域(组织)的反射光,以及一个透镜,用于将光聚焦到所需的组织深度并从同一区域收集回来。通过从同一采样区域收集数据,已将新的光学探头与商用激光多普勒探头进行了比较。我们的探头的结果显示,与现有的商用探头相比,检测血液灌注变化的准确性提高了15%。

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  • 来源
    《Sensors Journal, IEEE》 |2012年第6期|p.1861-1867|共7页
  • 作者

    Amini M.;

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