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首页> 外文期刊>Sensors and materials >Hemodynamic Performance Validation of Customized Handmade Trileaflet-valved Conduits Using Taguchi Method and Likelihood Degree Estimation
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Hemodynamic Performance Validation of Customized Handmade Trileaflet-valved Conduits Using Taguchi Method and Likelihood Degree Estimation

机译:使用Taguchi方法和似然度估算定制手工制作三叶树阀阀阀旋转导管的血流动力学性能验证

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摘要

Transcatheter pulmonary valve replacement (TPVR) is a technique for treating valvular heart diseases or dysfunctions without the need for open-heart surgery. Commercial valve stents, such as Epic™ valved stents or mechanical heart valves, can be used to solve the problems of narrowed or leaky pulmonary valves and also to improve regurgitation flow and heart pump efficiency (HPE). However, these prosthetic valves have limitations in terms of availability, durability, and stent size for children and for meeting the needs of special subjects. To be deemed fit for new clinical cases, handmade trileaflet-valved conduits (HTVCs) provide a promising strategy for designing stents using optimal design methods for customized specifications for child and adult patients. Before clinical applications, the functions of HTVCs need to verify hemodynamic statuses, such as the regurgitation fraction (RF), HPE, and pressure drop, under different heart rates (HR), blood flow volumes, and hypertension conditions. To reduce the number of experimental tests, the Taguchi method with signal-to-noise (S/N) ratios is used to validate the assigned optimal parameter designs, which can obtain good hemodynamic performance with the desired target goals of (1) RF ≤ 20% (minimizing the objective function) and (2) HPE ≥ 80% (maximizing the objective function). In contrast to commercial valve stents, such as Epic™ valved stent and mechanical heart valve, likelihood degree estimation is also employed to quantify the degree of valve performance and verify the quality of HTVCs.
机译:经导管肺瓣膜置换术(TPVR)是一种治疗瓣膜心脏病或功能障碍的技术,而无需露天手术。商业阀门支架,如EPIC™阀门支架或机械心阀,可用于解决肺阀的狭窄或漏水的问题,也可以改善流动流动和心脏泵效率(HPE)。然而,这些假肢阀对儿童的可用性,耐用性和支架规模的限制以及满足特殊科目的需求。要被视为新的临床案例,手工制作的三叶草阀(HTVC)为使用优化的设计方法为儿童和成人患者提供定制规格的定制设计提供了一个有希望的策略。在临床应用之前,HTVC的功能需要验证血液动力学状态,例如在不同的心率(HR),血流量和高血压条件下的再现分数(RF),HPE和压降。为了减少实验测试的数量,使用信号对噪声(S / N)比率的Taguchi方法用于验证分配的最佳参数设计,可以获得(1)RF≤的所需目标目标获得良好的血液动力学性能20%(最小化目标函数)和(2)HPE≥80%(最大化目标函数)。与商用阀支架相反,例如Epic™阀支架和机械心阀,似然度估计也用于量化阀门性能的程度并验证HTVC的质量。

著录项

  • 来源
    《Sensors and materials》 |2021年第1期|327-343|共17页
  • 作者单位

    Department of Electrical Engineering and Artificial Intelligence Application Research Center National Chin-Yi University of Technology Taichung City 41170 Taiwan Artificial Intelligence Application Research Center National Chin-Yi University of Technology Taichung City 41170 Taiwan;

    Department of Electrical Engineering and Artificial Intelligence Application Research Center National Chin-Yi University of Technology Taichung City 41170 Taiwan;

    Department of Electrical Engineering and Artificial Intelligence Application Research Center National Chin-Yi University of Technology Taichung City 41170 Taiwan;

    Department of Electrical Engineering and Artificial Intelligence Application Research Center National Chin-Yi University of Technology Taichung City 41170 Taiwan;

    Division of Cardiovascular Surgery Department of Surgery National Cheng Kung University Hospital College of Medicine National Cheng Kung University Tainan City 70101 Taiwan;

  • 收录信息 美国《科学引文索引》(SCI);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    pulmonary valve replacement; regurgitation fraction; heart pump efficiency; Taguchi method; signal-to-noise ratio; likelihood degree estimation;

    机译:肺瓣膜置换;反流分数;心脏泵效率;Taguchi方法;信噪比;似然估计;

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