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首页> 外文期刊>IEEE Journal of Solid-State Circuits >A Low-Power Integrated Circuit for a Wireless 100-Electrode Neural Recording System
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A Low-Power Integrated Circuit for a Wireless 100-Electrode Neural Recording System

机译：用于无线100电极神经记录系统的低功耗集成电路

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Recent work in field of neuroprosthetics has demonstrated that by observing the simultaneous activity of many neurons in specific regions of the brain, it is possible to produce control signals that allow animals or humans to drive cursors or prosthetic limbs directly through thoughts. As neuroprosthetic devices transition from experimental to clinical use, there is a need for fully-implantable amplification and telemetry electronics in close proximity to the recording sites. To address these needs, we developed a prototype integrated circuit for wireless neural recording from a 100-channel microelectrode array. The design of both the system-level architecture and the individual circuits were driven by severe power constraints for small implantable devices; chronically heating tissue by only a few degrees Celsius leads to cell death. Due to the high data rate produced by 100 neural signals, the system must perform data reduction as well. We use a combination of a low-power ADC and an array of "spike detectors" to reduce the transmitted data rate while preserving critical information. The complete system receives power and commands (at 6.5 kb/s) wirelessly over a 2.64-MHz inductive link and transmits neural data back at a data rate of 330 kb/s using a fully-integrated 433-MHz FSK transmitter. The 4.7times5.9 mm2 chip was fabricated in a 0.5-mum 3M2P CMOS process and consumes 13.5 mW of power. While cross-chip interference limits performance in single-chip operation, a two-chip system was used to record neural signals from a Utah Electrode Array in cat cortex and transmit the digitized signals wirelessly to a receiver
机译：神经修复领域的最新研究表明，通过观察大脑特定区域内许多神经元的同时活动，可以产生控制信号，使动物或人类通过思想直接驱动光标或假肢。随着神经假体装置从实验用途过渡到临床用途，需要在记录部位附近完全植入的放大和遥测电子设备。为了满足这些需求，我们开发了一种原型集成电路，用于从100通道微电极阵列进行无线神经记录。系统级架构和单个电路的设计均受到小型植入式设备的严格功率限制。长期仅将组织加热几摄氏度会导致细胞死亡。由于100条神经信号​​产生的高数据速率，因此系统还必须执行数据缩减。我们使用低功耗ADC和“尖峰检测器”阵列的组合来降低传输的数据速率，同时保留关键信息。完整的系统通过2.64 MHz感应链路无线接收功率和命令（以6.5 kb / s的速度），并使用完全集成的433 MHz FSK发射器以330 kb / s的数据速率将神经数据传回。 4.7×5.9 mm2芯片采用0.5um 3M2P CMOS工艺制造，功耗为13.5 mW。尽管跨芯片干扰限制了单芯片操作的性能，但使用了两芯片系统来记录来自猫皮层中犹他州电极阵列的神经信号，并将数字化信号无线传输至接收器

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