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Neurocognitive effects in welders exposed to aluminium: an application of the NPC test and NPC ranking methods

机译:铝焊工的神经认知作用:NPC测试和NPC分级方法的应用

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摘要

The aim of this study is to investigate the effects of exposure to aluminium on the cognitive sphere in a group of welders. Given the intrinsic complexity of the neurocognitive sphere, three different psychomotor variables were used for its investigation allowing the resulting problem to be naturally modelized into a multivariate framework and solved by a nonparametric combination of permutation tests (NPC test). In order to make the treated and control groups comparable, we also stratified the samples on the basis of a risk index that estimates the combined action of biological age and exposure time. Despite the fact that studies in the literature have reached conflicting results, our study highlights a significant drop in attention and memory performances in individuals exposed to aluminium. Finally, we identify a global criterion that summarises the information on the neurocognitive state by applying the non-parametric combination of dependent rankings method (NPC ranking).
机译:这项研究的目的是调查一组焊工中铝暴露对认知领域的影响。考虑到神经认知领域的内在复杂性,使用了三个不同的心理运动变量进行调查,从而将由此产生的问题自然地建模为多元框架,并通过排列检验(NPC检验)的非参数组合加以解决。为了使治疗组和对照组具有可比性,我们还根据风险指数对样本进行了分层,该指数评估了生物年龄和接触时间的综合作用。尽管文献中的研究得出了相互矛盾的结果,但我们的研究强调了铝暴露者的注意力和记忆力显着下降。最后,我们通过应用非参数组合的依赖排序方法(NPC排序),确定了一个概括有关神经认知状态信息的全局标准。

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