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Efficient estimation of variance components in nonparametric mixed-effects models with large samples

机译:大样本非参数混合效应模型中方差分量的有效估计

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摘要

Linear mixed-effects (LME) regression models are a popular approach for analyzing correlated data. Nonparametric extensions of the LME regression model have been proposed, but the heavy computational cost makes these extensions impractical for analyzing large samples. In particular, simultaneous estimation of the variance components and smoothing parameters poses a computational challenge when working with large samples. To overcome this computational burden, we propose a two-stage estimation procedure for fitting nonparametric mixed-effects regression models. Our results reveal that, compared to currently popular approaches, our two-stage approach produces more accurate estimates that can be computed in a fraction of the time.
机译:线性混合效应(LME)回归模型是一种用于分析相关数据的流行方法。已经提出了LME回归模型的非参数扩展,但是沉重的计算成本使得这些扩展对于分析大型样本不切实际。特别是,在处理大样本时,同时估计方差分量和平滑参数会带来计算难题。为了克服这一计算负担,我们提出了一个两阶段的估计程序来拟合非参数混合效应回归模型。我们的结果表明,与当前流行的方法相比,我们的两阶段方法可以产生更准确的估计值,而这些估计值可以在很短的时间内计算出来。

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