Minimally invasive colorectal resection is associated with a rapid and sustained decrease in plasma levels of epidermal growth factor (EGF) in the colon cancer setting

Michael J. Grieco; H. M. C. Shantha Kumara; Raymond Baxter; Nadav Dujovny; Matthew F. Kalady; Vesna Cekic; Martin Luchtefeld; Richard L. Whelan

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Minimally invasive colorectal resection is associated with a rapid and sustained decrease in plasma levels of epidermal growth factor (EGF) in the colon cancer setting

机译：在结肠癌环境中，微创结直肠切除术与血浆中表皮生长因子（EGF）的血浆水平持续快速降低有关

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Background Epidermal growth factor (EGF) stimulates tumor growth directly via tumor cell EGF receptors or indirectly via its proangiogenic effects. This study’s purpose was to determine the impact of minimally invasive colorectal resection (MICR) on postoperative (postop) plasma EGF levels in the colorectal cancer (CRC) and benign disease settings and to see if preoperative (PreOp) EGF levels are altered in cancer patients.

机译：背景技术表皮生长因子（EGF）直接通过肿瘤细胞EGF受体或通过其促血管生成作用间接刺激肿瘤生长。这项研究的目的是确定微创结直肠切除术（MICR）对结直肠癌（CRC）和良性疾病设置的术后（术后）血浆EGF水平的影响，并观察癌症患者的术前（PreOp）EGF水平是否改变。

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《Surgical Endoscopy》 |2010年第10期|p.2617-2622|共6页
作者
Michael J. Grieco; H. M. C. Shantha Kumara; Raymond Baxter; Nadav Dujovny; Matthew F. Kalady; Vesna Cekic; Martin Luchtefeld; Richard L. Whelan;
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正文语种 eng
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EGF; Colon cancer; Minimally invasive colectomy; Surgery;

机译：EGF;结肠癌;微创结肠切除术;手术;

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1. Minimally invasive colorectal resection is associated with a rapid and sustained decrease in plasma levels of epidermal growth factor (EGF) in the colon cancer setting. [J] . Grieco MJ, Shantha Kumara HM, Baxter R, Surgical Endoscopy . 2010,第10期

机译：在结肠癌环境中，微创结直肠切除术与血浆中表皮生长因子（EGF）的血浆水平快速持续下降有关。
2. Minimally invasive colorectal resection is associated with a transient increase in plasma hepatocyte growth factor levels early after surgery for colon cancer [J] . KumaraH.M.C.S., TohmeS.T., KimI.Y., Surgical innovation . 2011,第3期

机译：大肠癌微创切除术与结肠癌术后早期血浆肝细胞生长因子水平的短暂升高有关
3. Minimally invasive colon resection is associated with a transient increase in plasma sVEGFR1 levels and a decrease in sVEGFR2 levels during the early postoperative period [J] . H. M. C. Shantha Kumara, J. C. Cabot, A. Hoffman, Surgical Endoscopy . 2009,第4期

机译：术后早期，微创结肠切除术与血浆sVEGFR1水平的短暂升高和sVEGFR2水平的降低相关
4. Effect of preoperative cancer treatment on epidermal growth factor receptor (EGFR) receptor expression level in ABY-029 guided sarcoma surgery [C] . Xiaochun Xu, Kimberley S Samkoe, Eric R. Henderson Society of Photo-Optical Instrumentation Engineers;Conference on Molecular-Guided Surgery: Molecules, Devices, and Applications . 2020

机译：术前癌症治疗对ABY-029导向肉瘤手术中表皮生长因子受体（EGFR）受体表达水平的影响
5. Effects of the non-steriodal anti-inflammatory drug (NSAID) sulindac on epidermal growth factor receptor (EGFR) expression and signaling in colorectal cancer [D] . Pangburn, Heather Ann 2007

机译：非甾体类抗炎药（NSAID）舒林酸对大肠癌表皮生长因子受体（EGFR）表达和信号传导的影响
6. Colorectal cancer patients show decrease in cellular immunity and enhanced plasma level of transforming growth factor – beta and vascular endothelial growth factor (VEGF) [O] . Eva Zavadova, Vocka Michal, Konopasek Bohuslav, 2013

机译：大肠癌患者的细胞免疫力下降血浆转化生长因子-β和血管内皮生长因子（VEGF）水平升高
7. Colorectal cancer patients show decrease in cellular immunity and enhanced plasma level of transforming growth factor – beta and vascular endothelial growth factor (VEGF) [O] . Eva Zavadova, Vocka Michal, Konopasek Bohuslav, 2013

机译：大肠癌患者的细胞免疫力下降，血浆转化生长因子-β和血管内皮生长因子（VEGF）水平升高
8. Norepinephrine Decreases EGF (Epidermal Growth Factor) Binding in Primary Rat Hepatocyte Cultures [R] . Cruise, J. L. , Cotecchia, S. , Michalopoulos, G. 1986

机译：去甲肾上腺素降低原代大鼠肝细胞培养物中EGF（表皮生长因子）的结合

Minimally invasive colorectal resection is associated with a rapid and sustained decrease in plasma levels of epidermal growth factor (EGF) in the colon cancer setting

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