...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Surgical infections >Clinical Update on the Use of Moxifloxacin in the Treatment of Community-Acquired Complicated Intraabdominal Infections
【24h】

Clinical Update on the Use of Moxifloxacin in the Treatment of Community-Acquired Complicated Intraabdominal Infections

机译：使用莫西沙星治疗社区获得性复杂腹腔感染的临床更新

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Community-acquired complicated intraabdominal infections (cIAIs) present problems for clinicians and have substantial impact on hospital resources. Because of the polymicrobial nature of these infections, successful management of cIAIs depends on timely and appropriate use of antisepsis and antiinfective strategies. Methods: The literature pertinent to this article was reviewed.rnResults: The Surgical Infection Society and the Infectious Disease Society of America guidelines recommend a variety of single and combined antimicrobial therapies, including fluoroquinolone therapy, for prophylactic and definitive treatment of cIAIs with different severities. Moxifloxacin, a fluoroquinolone, demonstrates a broad spectrum of antimicrobial (including anaerobic) activity, good tissue penetration into the gastrointestinal tract, and a good tolerability profile. Clinical data also have demonstrated that moxifloxacin is effective as mono-therapy for patients with cIAIs. This review identifies the clinical issues impacting antimicrobial selection in cIAI and discusses data on the role of moxifloxacin in light of the current guidelines for management of these patients.rnConclusion: Moxifloxacin provides clinicians with a convenient monotherapy option for the treatment of mild-to-moderate cIAIs.
机译：背景：社区获得性复杂的腹腔内感染（cIAIs）给临床医生带来了问题，并对医院资源产生了重大影响。由于这些感染具有多种微生物性质，因此成功地治疗cIAI取决于及时，适当地使用防腐剂和抗感染策略。方法：综述了与本文相关的文献。结果：美国外科感染学会和传染病学会指南推荐了多种单一和联合抗菌疗法，包括氟喹诺酮疗法，用于不同严重度的cIAI的预防和确定性治疗。莫西沙星是一种氟喹诺酮，具有广谱的抗菌（包括厌氧）活性，良好的组织透入胃肠道和良好的耐受性。临床数据还证明，莫西沙星对cIAIs的患者有效。这篇综述鉴定了影响cIAI中抗菌药物选择的临床问题，并根据当前这些患者的治疗指南讨论了莫西沙星的作用数据。结论：莫西沙星为临床医生提供了一种治疗轻度至中度的便捷单药选择cIAI。

著录项

  • 来源
    《Surgical infections》 |2010年第5期|p.487-494|共8页
  • 作者

    William Cheadle; James T. Lee; Lena M. Napolitano; Ronald Lee Nichols;

  • 作者单位

    Department of Surgery, University of Louisville, Louisville, Kentucky Research and Development, Veterans Affairs Medical Center, Louisville, Kentucky;

    rnDepartment of Surgery (Retired), University of Minnesota Medical School, Minneapolis, Minnesota;

    rnAcute Care Surgery (Trauma, Burn, Critical Care, Emergency Surgery) Department of Surgery University of Michigan Health Systems 1500 E. Medical Center 1C421 UH SPC 5033 Ann Arbor, MI 48109-5033;

    rnDepartment of Surgery-Emeritus, Tulane School of Medicine, New Orleans, Louisiana;

  • 收录信息 美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号