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Clinical Analysis of 161 Cases of Surgical Treatment of Infective Endocarditis

机译:感染性心内膜炎手术治疗161例临床分析

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Objective: To evaluate the diagnostic criteria, surgical indications, and prognostic factors in the surgical treatment of infective endocarditis (IE). Methods: A total of 161 cases of post-operative IE treated at our hospital from January 2007 to December 2016 were included. The IE was diagnosed by the modified Duke criteria. Echocardiography and standard blood cultures were performed. These cases were divided into severe and non-severe adverse event groups. The association between prognostic factors and severe versus non-severe outcomes was examined using logistic regression. Results: Thirty patients (20.1%) with post-operative IE had positive pre-operative blood cultures, and 130 patients (80.7%) had valve vegetations. Four patients (2.5%) died within 30 days post-operatively. Twenty-two patients experienced severe adverse events. There were significant differences between the two groups regarding their serum albumin and creatinine concentrations, ejection fraction, and hospitalization, cardiopulmonary bypass, aortic cross-clamp, intensive care unit (ICU), and ventilation times (all p < 0.05). The bypass time, aortic cross-clamp time, and ICU time were identified as prognostic factors for severe adverse events. Conclusion: Echocardiography is an important diagnostic method for IE, and repeated tests might improve the sensitivity of diagnosis. Cardiac surgery seems to be an effective treatment for IE. Patient screening and reducing the operative time may improve the prognosis for patients who undergo surgical treatment for IE.
机译:目的:评估感染性心内膜炎(IE)的手术治疗的诊断标准,手术适应症和预后因素。方法:纳入我院2007年1月至2016年12月收治的161例术后IE患者。通过修改后的Duke标准诊断IE。进行超声心动图检查和标准血液培养。这些病例分为严重和非严重不良事件组。使用逻辑回归分析检查预后因素与严重与非严重预后之间的关系。结果:术后IE的30例患者(20.1%)术前血培养呈阳性,130例患者(80.7%)患有瓣膜植被。术后30天内有4名患者(2.5%)死亡。 22名患者发生了严重的不良事件。两组之间的血清白蛋白和肌酐浓度,射血分数以及住院,心肺旁路,主动脉夹钳,重症监护病房(ICU)和通气时间之间均存在显着差异(均p <0.05)。旁路时间,主动脉夹钳时间和ICU时间被确定为严重不良事件的预后因素。结论:超声心动图是一种重要的IE诊断方法,重复检查可能会提高诊断的敏感性。心脏手术似乎是治疗IE的有效方法。对接受IE手术治疗的患者进行筛查和减少手术时间可以改善其预后。

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