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Silver-gallium antimicrobial technology kills bacterial biofilms

机译：银镓抗微生物技术杀死细菌生物膜

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Imbed Biosciences of Fitchburg, Wisconsin, USA, is enhancing its silver-coating technology with the addition of gallium ions to provide improved antibacterial efficacy for wound dressings used to treat severe burns and diabetic skin ulcers. The addition of gallium ions aims to improve the dressing's antimicrobial efficacy against biofilms that can shield bacteria from antibiotics. Imbed Biosciences Vice President, Research and Development Gaurav Pranami said the company has carried out fundamental research to formulate the design principles for pairing silver ions with gallium. He explained that the bacteria in biofilms require iron for their metabolic activities. Since gallium and iron are similar in ionic radii and charge, bacteria will take-up gallium. However, gallium cannot be reduced by the bacteria like iron, so they atrophy and the biofilm breaks-up.This renders the bacteria in and underlying the biofilm more vulnerable to the silver.
机译：美国威斯康星州威斯康星州富思堡的Biosciences正在增强其银涂技术，并加入镓离子以提供用于治疗严重灼伤和糖尿病皮肤溃疡的伤口敷料的改善抗菌效果。加入镓离子旨在改善敷料对生物膜的抗微生物功效，可以保护抗生素的细菌。默认的Biosciences副总裁Gaurav Pranami表示，该公司已经开展了基本研究，以制定与镓配对银离子的设计原则。他解释说，生物膜中的细菌需要铁代谢活动。由于镓和铁在离子半径和电荷中类似，细菌将占用镓。然而，镓不能被熨斗等细菌减少，因此它们萎缩和生物膜突破。这使得生物膜的细菌和底层脆弱地易受银。

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