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Chitosan-manuka honey composite wound dressings

机译：壳聚糖-麦卢卡蜂蜜复合伤口敷料

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摘要

This study is focused on the development of bioactive composite wound dressings with desirable wound healing properties using needle punched nonwovens, chitosan, and manuka honey. 3 different methods using film, halftone, and dip and dry techniques, were devised to prepare chitosan-honey wound dressings with viscose and bamboo nonwovens as secondary layer and chitosan-manuka honey as primary layer. All dressings prepared were evaluated for their effectiveness as wound dressing and characterized. The results indicate that the weight and thickness of almost all the samples are comparable. The film dressings showed a higher value of air permeability and water vapor transmission of 55 cm~3/cm~2/s and 1,700 g/m~2/day.The swelling ratio of film dressings was 283%. Even though dip and dry dressings showed better antimicrobial activity and higher tensile strength, their elongation is low compared to film dressings. Halftone treated samples show poor coating in the morphological observation. Hence, from the obtained results, it can be concluded that the film wound dressings show considerable advantage over halftone and dip and dry dressings.
机译：这项研究的重点是使用针刺无纺布，壳聚糖和麦卢卡蜂蜜开发具有理想伤口愈合性能的生物活性复合伤口敷料。设计了三种使用薄膜，半色调，浸入和干燥技术的不同方法来制备以粘胶和竹无纺布为第二层，以壳聚糖-麦卢卡蜂蜜为第一层的壳聚糖蜂蜜伤口敷料。评价所有制备的敷料作为伤口敷料的有效性并进行表征。结果表明几乎所有样品的重量和厚度都是可比的。薄膜敷料的透气度和水蒸气透过率较高，分别为55 cm〜3 / cm〜2 / s和1,700 g / m〜2 /天，薄膜敷料的溶胀率为283％。尽管浸蘸和干敷料显示出更好的抗菌活性和更高的拉伸强度，但与薄膜敷料相比它们的伸长率仍然较低。经半色调处理的样品在形态观察中显示出较差的涂层。因此，从获得的结果可以得出结论，薄膜伤口敷料相对于半色调和浸润和干敷料显示出相当大的优势。

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  • 来源
    《Technische Textilien》 |2017年第5期|E283-E284|共2页
  • 作者

    L. Sasikala; Bhaarathi Dhurai; S. Sundaresan;

  • 作者单位

    Kumaraguru College ofTechnology, Coimbatore/India;

    Kumaraguru College ofTechnology, Coimbatore/India;

    Kumaraguru College ofTechnology, Coimbatore/India;

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