GermStabbing Particles

James Hedrick

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GermStabbing Particles

机译：刺刺颗粒

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Nanoparticles designed to disrupt the cell membranes of a large group of pathogens, including multidrug-resistant Staphylo coccus aureus, cause the cells to burst open but don't harm human red blood cells. WHY IT MATTERS: Because the nanoparticles don't target a specific genetic pathway, researchers hope bacteria will be slow to develop resistance to them. Previous attempts to make polymers that kill microbes by poking holes in cell membranes have raised safety concerns because they tend to harm some animal cells, too, or they haven't worked as well in the body as they did in a test tube.

机译：旨在破坏包括多种多药耐药性金黄色葡萄球菌在内的大量病原体细胞膜的纳米颗粒，可以使细胞破裂，但不会伤害人类红细胞。为何要注意：由于纳米粒子不针对特定的遗传途径，因此研究人员希望细菌对它们产生抵抗力的速度较慢。先前尝试通过在细胞膜上戳孔来杀死微生物的聚合物的尝试引起了安全方面的关注，因为它们也容易损害某些动物细胞，或者它们在体内的作用不如在试管中那样好。

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《Technology Review》 |2011年第4期|p.84|共1页
作者
James Hedrick;
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机译：刺刺颗粒
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3. Preparation and properties of inhalable nanocomposite particles: Effects of the size, weight ratio of the primary nanoparticles in nanocomposite particles and temperature at a spray-dryer inlet upon properties of nanocomposite particles [J] . Tomoda K, Ohkoshi T, Nakajima T, Colloids and Surfaces, B. Biointerfaces . 2008,第1期

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GermStabbing Particles

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