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Antibacterial evaluation of cotton textile treated by trialkoxysilane compounds with antimicrobial moiety

机译:带有抗菌部分的三烷氧基硅烷化合物处理的棉纺织品的抗菌评价

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Compounds based upon aldehyde functionalities or long chain quaternary ammonium functionalities constitute twonmajor classes of antimicrobial materials. The antibacterial activities of these two classes of compounds were evaluated innthe unbound (free compound) aqueous suspension and in the bound surface-treated cotton textile against E. coli. After anone hour incubation, the minimum lethal concentration of AEM 5700, a commercially available quaternary ammoniumnfunctional silane from Aegis Environments, was found to be 84 mg/g in the deionized water. The salinity of the test mediansignificantly affected the antibacterial activity of AEM 5700 free compound. The minimum lethal concentration wasnincreased to 8000 mg/g in the artificial seawater. Inactivation against E. coli of either free butyraldehyde or undecanylaldehydenfunctional triethoxysilylane in the deionized water was not observed. Cotton textile treated with various concentrationsnof AEM 5700 showed a two-stage antibacterial behavior when immersed in the deionized water. The highernactivity in the first stage was due to the combined action of the leachate and the surface-bound AEM 5700, whereas thenactivity in the second-stage was caused by the contact between the surface-bound AEM 5700 and E. coli. This analysis wasnconfirmed when the AEM 5700 treated cotton textile was tested in the artificial seawater. The leachate in the artificialnseawater had no activity. The first-stage antibacterial behavior was not observed. Only the contact between the surfaceboundnAEM 5700 and E. coli contributed to about a one log reduction plateau with time. For cotton textile treated byneither of the examined trialkoxysilylaldehyde compounds, inactivation against E. coli was not found.
机译:基于醛官能度或长链季铵官能度的化合物构成了两大类抗菌材料。在未结合的(游离化合物)水性悬浮液中和结合的经表面处理的棉纺织品中,对这两类化合物的抗菌活性进行了评估,以抵抗大肠杆菌。温育一个小时后,发现去离子水中AEM 5700(可从Aegis Environments购买的季铵官能硅烷)的最小致死浓度为84 mg / g。测试中位数的盐度显着影响不含AEM 5700的化合物的抗菌活性。人工海水中的最低致死浓度提高到8000 mg / g。在去离子水中未观察到游离丁醛或十一烷醛-n官能的三乙氧基甲硅烷基烷对大肠杆菌的灭活。 AEM 5700的各种浓度的棉纺织品浸入去离子水中后均表现出两阶段的抗菌性能。第一阶段的较高活性是由于沥滤液和表面结合的AEM 5700的共同作用,而第二阶段的活性则是由于表面结合的AEM 5700和大肠杆菌之间的接触引起的。当在人工海水中对经AEM 5700处理的棉纺织品进行测试时,该分析未被确认。人造海水中的渗滤液没有活性。没有观察到第一阶段的抗菌行为。随着时间的推移,仅surfaceboundnAEM 5700和大肠杆菌之间的接触有助于减少约一个log的平稳期。对于未用任何一种经检测的三烷氧基甲硅烷基醛化合物处理的棉纺织品,未发现对大肠杆菌具有灭活作用。

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