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Multilamellar Liposomes Including Cholesterol as Carriers of Azobenzene Disperse Dyes in Wool Dyeing

机译:多层脂质体,包括胆固醇作为羊毛染色中偶氮苯分散染料的载体

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摘要

We have investigated multilamellar lipid vesicles (MLV) of defined size (400 nm) containing increasing amounts of cholesterol (CH) as carriers of azobenzene disperse dyes to wool fibers. The liposomes are made from egg phosphatidylcholine (PC) and contain CI Disperse Orange 1 at different PC : CH relative concentrations. The physical stability of these systems is assessed by measuring the mean vesicle size distribution of the vesicle suspensions after preparation and during the dyeing process. Kinetic aspects involve dye adsorption and bonding on untreated wool samples by means of MLV liposomes at different PC: CH ratios. This process leads to the controlled exhaustion of dye in wool samples, which depends on the liposome lipid concentration. Increasing amounts of CH in bilayers result in a slight decrease in the dye exhaustion, although improving the total amounts of dye bonded to wool fibers. The optimum balance is reached for the maximum concentration of CH in bilayers, using the dye/ lipid weight ratio corresponding to the maximum encapsulation efficiency of the dye. This technological application also improves the dispersing efficiency of these systems with respect to the use of conventional dispersing agents.
机译:我们已经研究了确定大小(400 nm)的多层脂质囊泡(MLV),其中包含越来越多的胆固醇(CH)作为偶氮苯分散染料在羊毛纤维上的载体。脂质体由卵磷脂酰胆碱(PC)制成,并包含相对于PC:CH相对浓度不同的CI Disperse Orange 1。这些系统的物理稳定性通过在制备后和染色过程中测量囊泡悬浮液的平均囊泡尺寸分布来评估。动力学方面涉及染料吸附和通过MLV脂质体以不同的PC:CH比在未处理的羊毛样品上结合。此过程导致羊毛样品中染料的受控消耗,这取决于脂质体脂质的浓度。尽管增加了与羊毛纤维结合的染料总量,但双层中CH含量的增加导致染料消耗略有减少。使用与染料的最大包封效率相对应的染料/脂质重量比,可以使双层中CH的最大浓度达到最佳平衡。相对于常规分散剂的使用,该技术应用还提高了这些系统的分散效率。

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