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Pulsed laser deposition of biocompatible polymers: a comparative study in case of pullulan

机译:生物相容性聚合物的脉冲激光沉积:支链淀粉的比较研究

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摘要

We report some results of a comparison between thin films of pullulan biopolymer obtained by pulsed laser deposition (PLD) and matrix-assisted pulsed laser evaporation (MAPLE). In experiments we used a KrF~* laser source generating pulses of 248 nm and 20 ns pulse duration. We demonstrate by Fourier transformed infrared spectroscopy (FTIR) that MAPLE is more appropriate than conventional PLD for transfer with high structural fidelity of biopolymers from target to substrate. In case of MAPLE, besides FTIR spectra, atomic force microscopy micrographs and scanning electron microscopy images prove that the film composition and structure strongly depend on the solvent used for the targets preparation: distilled water, ethylene glycol, ethanol, tert-butanol and dimethyl sulfoxide. Our best results for pullulan deposition were obtained using dimethyl sulfoxide as a solvent. This is the first report of successful MAPLE deposition of this material as thin films.
机译:我们报告通过脉冲激光沉积(PLD)和基质辅助脉冲激光蒸发(MAPLE)获得的支链淀粉生物聚合物薄膜之间比较的一些结果。在实验中,我们使用KrF〜*激光源生成248 nm的脉冲和20 ns的脉冲持续时间。我们通过傅立叶变换红外光谱(FTIR)证明,MAPLE比常规PLD更适合以高结构保真度从目标到底物转移生物聚合物。对于MAPLE,除FTIR光谱外,原子力显微镜照片和扫描电子显微镜图像证明膜的组成和结构在很大程度上取决于目标制备所用的溶剂:蒸馏水,乙二醇,乙醇,叔丁醇和二甲基亚砜。使用二甲基亚砜作为溶剂可获得支链淀粉沉积的最佳结果。这是该材料以薄膜成功进行MAPLE沉积的首次报道。

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