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Brain Water Content: a Misunderstood Measurement?

机译:大脑含水量:一个被误解的测量方法?

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摘要

Brain edema is a major contributor to poor outcome following ischemic and hemorrhagic stroke. In animal models, edema has historically been quantified as a change in brain water content expressed as a percentage of wet weight (% water content). As described in this communication, this number can be misleading, as “small” changes in percentage of brain water content actually reflect much bigger changes in brain swelling. Using either water content, expressed as grams per gram of dry weight, or a measure of brain swelling better reflect the impact of edema after stroke and brain injury.
机译:脑水肿是缺血性和出血性中风后不良预后的主要原因。在动物模型中,水肿历来被量化为脑含水量的变化,以湿重的百分比(含水量%)表示。如本来文所述,这个数字可能会产生误导,因为脑含水量的“小”变化实际上反映了脑肿胀的大得多的变化。使用以克/克干重表示的水含量或脑肿胀的测量方法可以更好地反映中风和脑损伤后水肿的影响。

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