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Atomic force microscopy wear characterization of biomedical polymer coatings

机译：生物医学聚合物涂层的原子力显微镜磨损表征

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摘要

Atomic force microscopy (AFM) has become established as a powerful and versatile tool for investigating local mechanical properties. In addition, through the AFM tip-sample interaction, it has become possible to study the effects of perturbations and modifications to the surface of soft samples, such as polymers. The accurate knowledge of their response to continuous AFM scanning could help to design new materials having desirable mechanical properties. In this paper, we present the results obtained by applying a new methodology to investigate wear properties on two different type of polymer, poly(methyl-methacrylate) and poly(L-lactic acid). These polymers have been widely employed in biomedical applications and have recently been considered as good candidates for coronary metallic stent coatings.
机译：原子力显微镜（AFM）已成为研究局部机械性能的强大而多功能的工具。此外，通过AFM尖端样品相互作用，研究扰动和改性对软质样品（如聚合物）表面的影响成为可能。关于它们对连续AFM扫描的响应的准确了解可以帮助设计具有所需机械性能的新材料。在本文中，我们介绍了通过应用新方法研究两种不同类型的聚合物（聚甲基丙烯酸甲酯）和聚（L-乳酸）的磨损性能而获得的结果。这些聚合物已被广泛用于生物医学应用，并且最近被认为是冠状金属支架涂层的良好候选者。

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