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首页> 外文期刊>Tropical Animal Health and Production >Multiple anthelmintic resistance on a goat farm in Hawassa (southern Ethiopia)
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Multiple anthelmintic resistance on a goat farm in Hawassa (southern Ethiopia)

机译：Hawassa（埃塞俄比亚南部）的一个山羊农场对多种驱虫药的抗药性

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A study was conducted to determine the presence of anthelmintic resistance on Hawassa University goat farm in southern Ethiopia. The 180 goats were stratified by age and sex and randomly assigned to treatment groups (albendazole, tetramisole and ivermectin and untreated control). Each treatment group included 15 goats and treatments were administered according to weight of each goat with 7.5 mg/kg bw albendazole, 22.5 mg/kg bw tetramisole and 0.2 mg/kg bw ivermectin dose rates recommended by scientists. Faecal samples were collected on day 0 before treatment, and again on day 12 post treatment. Efficacy of all the drugs was assessed on day 12 post treatment by faecal egg count reduction test (FECRT). Multiple anthelmintic resistance in Haemonchus spp. against albendazole, tetramisole and ivermectin was recorded in all age categories of the goats. Likewise, Trichostrongylus/Teladorsagia spp. showed resistance against ivermectin. Coprocultures from all pre- and post-treatments revealed the predominance of Haemonchus spp. Resistance against anthelmintics is attributed to the high frequency of treatment and low dosage of treatment practices on the farm. Large scale studies, however, are needed to assess the current status of anthelmintic resistance against the most commonly used anthelmintics in different agroecology, species of animals and management systems in Ethiopia.
机译：进行了一项研究，以确定埃塞俄比亚南部的Hawassa University山羊农场的驱虫药耐药性。将180只山羊按年龄和性别分层，并随机分为治疗组（阿苯达唑，丁苯甲醚和伊维菌素以及未治疗的对照组）。每个治疗组包括15只山羊，并根据科学家的建议按每只山羊的体重给予7.5 mg / kg bw阿苯达唑，22.5 mg / kg bw丁咪唑和0.2 mg / kg bw伊维菌素剂量率进行治疗。在治疗前第0天和治疗后第12天收集粪便样品。在治疗后第12天通过粪便卵数减少试验（FECRT）评估所有药物的功效。 Haemonchus spp中的多种驱虫抗药性。在所有年龄段的山羊中均记录有对阿苯达唑，丁苯甲醚和伊维菌素的抗性。同样，Trichostrongylus / Teladorsagia spp。对伊维菌素表现出耐药性。所有前处理和后处理的共培养表明，Haemonchus spp占主导地位。对驱虫药的抵抗力归因于农场的高频率治疗和低剂量的治疗方法。但是，需要进行大规模研究，以评估埃塞俄比亚不同农业生态，动物物种和管理系统对最常用驱虫药的驱虫抗药性现状。

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