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{1742-271X}[20122003](0005)

机译：{1742-271X} [20122003]（0005）

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摘要

Introduction This study evaluated the role of high-resolution ultrasonography in the assessment of pigmented skin lesions in correlation with clinico-pathological findings to predict malignant potential with high sensitivity and specificity. nnMethods A prospective cross-sectional study was carried out in 124 cases of pigmented skin lesions by using variable frequency (6–18 MHz) high-resolution ultrasonography and colour Doppler over a period of 14 months in Central Hospital, South Central Railway, Hyderabad, India. The correlation between sonographic parameters (greyscale imaging characteristics and vascular flow on colour Doppler) and pathological parameters (malignant and benign) were statistically analysed. nnResults For predicting malignancy, the presence of vascular flow on colour Doppler had good overall accuracy, specificity and negative predictive value but relatively low sensitivity and positive predictive value (respectively, 91%, 94%, 94%, 81% and 78%). However, greyscale imaging characteristics to predict malignancy had low overall accuracy, specificity and positive predictive value but high sensitivity and negative predictive value (respectively, 54%, 34%, 26%, 85% and 89%). There was a significant positive association between vascular flow on Doppler and malignancy (P = 0.0001) but the correlation between greyscale imaging findings and malignancy is not statistically significant (P = 0.0603). nnConclusions High-resolution sonographic imaging is useful in non-invasive monitoring of pigmented lesions at risk and screening of pigmented lesions suspected of malignancy to give relevant information about the extent and nature of the disease and to stratify the high risk cases for surveillance and planning of the treatment.
机译：引言这项研究结合临床病理结果评估了高分辨率超声检查在评估色素沉着皮肤病变中的作用，从而以高灵敏度和特异性预测了恶性潜能。 nn方法采用可变频率（6–18 MHz）高分辨率超声检查和彩色多普勒超声对124例皮肤色素沉着病变进行了为期14个月的前瞻性横断面研究，印度。统计学分析超声参数（灰度成像特征和彩色多普勒上的血管流量）与病理参数（恶性和良性）之间的相关性。结果对于预测恶性肿瘤，彩色多普勒仪上的血管血流总体准确性，特异性和阴性预测值均良好，但敏感性和阳性预测值相对较低（分别为91％，94％，94％，81％和78％）。然而，用于预测恶性肿瘤的灰度成像特征具有较低的总体准确性，特异性和阳性预测值，但具有较高的敏感性和阴性预测值（分别为54％，34％，26％，85％和89％）。多普勒血流与恶性肿瘤之间存在显着的正相关（P = 0.0001），但是灰度影像学发现与恶性肿瘤之间的相关性在统计学上不显着（P = 0.0603）。结论高分辨超声成像可用于无创性监测处于危险状态的色素性病变和筛查疑似恶性肿瘤的色素性病变，以提供有关疾病范围和性质的相关信息，并对高危病例进行监测和计划分层治疗。

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  • 来源
    《Ultrasound》 |2012年第3期|p.155-160|共6页
  • 作者

    Anitha Mandava1⇓ Rajyalaxmi Konathan2 and Krishnaveni Neelala3;

  • 作者单位

    1Department of Radiodiagnosis, Central Hospital, Lalaguda, South Central Railway, Secunderabad, Andhra Pradesh 500017, India 2Department of Dermatovenereology, Central Hospital, Lalaguda, South Central Railway, Secunderabad, Andhra Pradesh 500017, India 3Department of Pathology, Central Hospital, Lalaguda, South Central Railway, Secunderabad, Andhra Pradesh 500017, India;

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  • 正文语种 eng
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  • 关键词

    High-resolution ultrasonography pigmented skin lesions colour Doppler;

    机译：高分辨率超声检查色素沉着的皮肤病变彩色多普勒;

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