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Is there a co-association between renal or retroperitoneal tumours and scrotal varicoceles? A systematic review

机译:肾脏或腹膜后肿瘤与阴囊精索静脉曲张之间是否存在关联?系统评价

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摘要

Scrotal varicoceles, which are relatively common, are sometimes caused by venous flow disturbance resulting from a renal or retroperitoneal tumour. Consequently, it is common practice to perform extended renal and retroperitoneal scans following varicocele identification. The aim of this systematic review was to determine the extent of the co-association between renal or retroperitoneal tumours and scrotal varicoceles using primary research literature. We conducted a search of 11 electronic databases; hand-searched five relevant textbooks; and conducted forward- and backward-citation searches of included articles. Articles that were included were assessed for research quality and data extracted. Twenty-four articles were found, comprising 19 case reports and five case series, reporting 35 cases in total. All cases had both a varicocele and a tumour (renal, retroperitoneal or other). We found no cohort or case–control studies. In conclusion, case reports and case series are susceptible to significant publication bias and the lack of any cohort or case–control studies meant that it was not possible to establish the extent of the co-association between renal or retroperitoneal tumours and scrotal varicoceles. It was not possible to estimate the value of conducting an extended scan in patients with scrotal varicoceles. Research is needed, particularly of a cohort or case-control design and including a robust sampling method, to examine the extent of any co-association. Meanwhile, extended renal or retroperitoneal scans should be undertaken when diagnosing all varicoceles, regardless of patient age, until this research is completed.
机译:阴囊静脉曲张相对较常见,有时是由肾脏或腹膜后肿瘤引起的静脉血流紊乱引起的。因此,通常的做法是在精索静脉曲张鉴别后进行扩大的肾脏和腹膜后扫描。本系统综述的目的是使用主要的研究文献来确定肾或腹膜后肿瘤与阴囊静脉曲张之间的关联程度。我们搜索了11个电子数据库;手工搜索了五本相关的教科书;并对收录的文章进行了前后引用搜索。评估纳入的文章的研究质量和提取的数据。共找到二十四篇文章,其中包括19个案例报告和五个案例系列,总共报告35个案例。所有病例均患有精索静脉曲张和肿瘤(肾脏,腹膜后或其他)。我们没有队列研究或病例对照研究。总之,病例报告和病例系列容易受到明显的发表偏见的影响,而缺乏任何队列研究或病例对照研究意味着不可能确定肾脏或腹膜后肿瘤与阴囊静脉曲张之间的关联程度。无法估计在阴囊静脉曲张患者中进行扩展扫描的价值。需要进行研究,尤其是队列研究或病例对照设计,并包括可靠的抽样方法,以研究任何协同关联的程度。同时,在诊断所有精索静脉曲张时,无论患者年龄如何,都应进行扩展的肾脏或腹膜后扫描,直至完成本研究。

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  • 来源
    《Ultrasound》 |2012年第4期|p.182-191|共10页
  • 作者单位

    1Calderdale and Huddersfield NHS Foundation Trust, Ultrasound Department, Huddersfield Royal Infirmary, Acre Street, Huddersfield HD3 3EA, UK 2University of Leeds, Academic Unit of Diagnostic Imaging, Leeds Institute of Diagnostics & Therapeutics, School of Healthcare, G.16, Baines Wing, Leeds LS2 9JT, UK 3University of York, Department of Health Sciences, York YO10 5DD, UK;

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  • 正文语种 eng
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  • 关键词

    Varicocele renal tumour retroperitoneal tumour systematic review;

    机译:精索静脉曲张肾肿瘤腹膜后肿瘤系统评​​价;

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